trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Base Information

Chemical Name:trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate
CAS No.:1201648-49-8
Molecular Formula:C₂₄H₃₁ClN₂O₄Si
Molecular Weight:475.06
Hs Code.:

Synonyms:trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

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Chemical Property of trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

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Technology Process of trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

There total 3 articles about trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-77-4
chloro-trimethyl-silane

: 1058165-14-2
R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetic acid

: 1201648-49-8
trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: In tetrahydrofuran; for 1.5h;

Reference yield:

: 163837-57-8
(R)-(4-chlorophenyl)(phenyl)methylamine

: 1201648-49-8
trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / 3 h / Reflux

1.2: 60 °C / Reflux

2.1: tetrabutylammomium bromide / dimethyl sulfoxide / 10 h

3.1: tetrahydrofuran / 1.5 h

With tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dimethyl sulfoxide;

Reference yield:

: 300543-56-0
(R)-1-((4-chlorophenyl)(phenyl)methyl)piperazine

: 1201648-49-8
trimethylsilyl R-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-oxoethoxy)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutylammomium bromide / dimethyl sulfoxide / 10 h

2: tetrahydrofuran / 1.5 h

With tetrabutylammomium bromide; In tetrahydrofuran; dimethyl sulfoxide;