4-Hydroxythiobenzamide

Base Information Edit

Chemical Name:4-Hydroxythiobenzamide
CAS No.:25984-63-8
Molecular Formula:C7H7NOS
Molecular Weight:153.205
Hs Code.:29242990
European Community (EC) Number:674-712-0
UNII:ZZ8JR2736Y
DSSTox Substance ID:DTXSID40420703
Nikkaji Number:J2.383.239I
ChEMBL ID:CHEMBL2441358
Mol file:25984-63-8.mol

Synonyms:4-Hydroxythiobenzamide;25984-63-8;4-hydroxybenzothioamide;4-hydroxy thiobenzamide;4-hydroxybenzenecarbothioamide;BENZENECARBOTHIOAMIDE, 4-HYDROXY-;4-Hydroxybenzene-1-carbothioamide;ZZ8JR2736Y;MFCD04973332;p-hydroxythiobenzamide;4-hydroxy-thiobenzamide;4-hydroxythio-benzamide;UNII-ZZ8JR2736Y;SCHEMBL469734;4-[amino(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one;CHEMBL2441358;DTXSID40420703;VDTNKXSVUGXUOJ-UHFFFAOYSA-N;HMS1728O12;4-hydroxythiobenzamide, AldrichCPR;BCP12826;BBL010014;STK801400;AKOS000200442;AB21285;AC-5907;CS-W018071;GS-3132;SY030992;A5174;AM20090771;FT-0600967;H1308;EN300-13412;A818133;J-515515;Z90124534;4-[amino(mercapto)methylidene]-1-cyclohexa-2,5-dienone;4-[azanyl(sulfanyl)methylidene]cyclohexa-2,5-dien-1-one

Suppliers and Price of 4-Hydroxythiobenzamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Hydroxythiobenzamide
25g
$ 205.00

TCI Chemical
4-Hydroxythiobenzamide >98.0%(HPLC)(N)
25g
$ 81.00

TCI Chemical
4-Hydroxythiobenzamide >98.0%(HPLC)(N)
5g
$ 27.00

SynChem
4-Hydroxythiobenzamide 95+%
1 g
$ 15.00

SynChem
4-Hydroxythiobenzamide 95+%
10 g
$ 75.00

SynChem
4-Hydroxythiobenzamide 95+%
5 g
$ 45.00

Matrix Scientific
4-Hydroxythiobenzamide 95+%
25g
$ 178.00

Matrix Scientific
4-Hydroxythiobenzamide 95+%
100g
$ 435.00

Frontier Specialty Chemicals
4-Hydroxythiobenzamide 98%
5g
$ 90.00

Crysdot
4-Hydroxybenzothioamide 98%
1000g
$ 176.00

Total 206 raw suppliers

Chemical Property of 4-Hydroxythiobenzamide Edit

Chemical Property:

Appearance/Colour:Grey white powder
Vapor Pressure:0mmHg at 25°C
Melting Point:181-185℃
Refractive Index:1.702
Boiling Point:320.394 °C at 760 mmHg
PKA:9.24±0.26(Predicted)
Flash Point:147.57 °C
PSA：78.34000
Density:1.339 g/cm³
LogP:1.72670
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:153.02483502
Heavy Atom Count:10
Complexity:130

Purity/Quality:

98% ^*data from raw suppliers

4-Hydroxythiobenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 20/21/22-36/37/38-43-22
Safety Statements: 26-36/37/39-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=S)N)O
Uses 4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease. febuxostat intermediate

Technology Process of 4-Hydroxythiobenzamide

There total 9 articles about 4-Hydroxythiobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.57%

: 767-00-0
4-cyanophenol

: 25984-63-8
4-hydroxythiobenzamide

Guidance literature:: 4-cyanophenol; With sodium hydrogensulfide; In water; at 20 ℃; for 0.5h;

With hydrogen sulfide; at 70 ℃; for 5.91667 - 6h; under 2068.65 - 2896.11 Torr;