C₂₈H₂₈BrN₃O₅

Base Information

• Chemical Name: C₂₈H₂₈BrN₃O₅
• CAS No.: 1147077-78-8
• Molecular Formula: C₂₈H₂₈BrN₃O₅
• Molecular Weight: 566.451
• Mol file: 1147077-78-8.mol

Synonyms:C₂₈H₂₈BrN₃O₅

Chemical Property of C₂₈H₂₈BrN₃O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₈BrN₃O₅

There total 6 articles about C₂₈H₂₈BrN₃O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

C28H29N3O5 (1147077-77-7) → C28H28BrN3O5 (1147077-78-8)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In benzene; for 16h; Reflux;

DOI:10.1021/jm100971t

Reference yield:

2,3-dihydro-6-methyl-1H-inden-1-one (24623-20-9) → C28H28BrN3O5 (1147077-78-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide / ethanol / 3 h

2.1: sodium hydroxide / ethanol / 0.5 h / Inert atmosphere

2.2: 14.5 h / 80 °C

2.3: 4 h / 100 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere

4.1: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 16 h / Reflux

With N-Bromosuccinimide; potassium carbonate; sodium hydroxide; dibenzoyl peroxide; In ethanol; N,N-dimethyl-formamide; benzene;

DOI:10.1021/jm100971t

Reference yield:

benzaldehyde (100-52-7) → C28H28BrN3O5 (1147077-78-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide / ethanol / 3 h

2.1: sodium hydroxide / ethanol / 0.5 h / Inert atmosphere

2.2: 14.5 h / 80 °C

2.3: 4 h / 100 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 18 h / 20 °C / Inert atmosphere

4.1: N-Bromosuccinimide; dibenzoyl peroxide / benzene / 16 h / Reflux

With N-Bromosuccinimide; potassium carbonate; sodium hydroxide; dibenzoyl peroxide; In ethanol; N,N-dimethyl-formamide; benzene;

DOI:10.1021/jm100971t

upstream raw materials:

C₂₈H₂₉N₃O₅

2-amino-8-methyl-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one

2,3-dihydro-6-methyl-1H-inden-1-one

2-benzylidene-6-methylindan-1-one

Downstream raw materials:

2-amino-8-(bromomethyl)-4-phenyl-5H-indeno[1,2-d]-pyrimidin-5-one

C₂₈H₂₇N₃O₆

2-((bis-tert-butoxycarbonyl)amino)-5-oxo-4-phenyl-5H-indeno[1,2-d]pyrimidine-8-carboxylic acid

2-amino-8-nicotinoyl-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one