tpOXD-mTP

Base Information

• Chemical Name: tpOXD-mTP
• CAS No.: 1334124-94-5
• Molecular Formula: C₄₂H₃₈N₄O₂
• Molecular Weight: 630.789
• Mol file: 1334124-94-5.mol

Synonyms:tpOXD-mTP

Chemical Property of tpOXD-mTP

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tpOXD-mTP

There total 2 articles about tpOXD-mTP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-(3-bromophenyl)-5-(4-(tert-butyl)phenyl)-1,3,4-oxadiazole (328285-14-9) + 4,4,5,5-tetramethyl-2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,2-dioxaborolane (196212-27-8) → tpOXD-mTP (1334124-94-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; potassium carbonate; In dimethyl sulfoxide; at 80 - 120 ℃; Inert atmosphere;

DOI:10.1039/c2jm33376g

Reference yield:

3-cyanobromobenzene (6952-59-6) → tpOXD-mTP (1334124-94-5)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide; acetic acid / butan-1-ol / 48 h / Reflux

2: pyridine / 24 h / 120 °C

3: bis-triphenylphosphine-palladium(II) chloride; potassium acetate; potassium carbonate / dimethyl sulfoxide / 80 - 120 °C / Inert atmosphere

With pyridine; bis-triphenylphosphine-palladium(II) chloride; sodium azide; potassium acetate; potassium carbonate; acetic acid; In dimethyl sulfoxide; butan-1-ol;

DOI:10.1039/c2jm33376g

upstream raw materials:

2-(3-bromophenyl)-5-(4-(tert-butyl)phenyl)-1,3,4-oxadiazole

4,4,5,5-tetramethyl-2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,2-dioxaborolane

3-cyanobromobenzene