17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

Base Information

Chemical Name:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan
CAS No.:1032281-06-3
Molecular Formula:C₂₈H₃₃NO₄
Molecular Weight:447.574
Hs Code.:

Synonyms:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

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Chemical Property of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

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Technology Process of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

There total 2 articles about 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1032281-02-9
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

: 1032281-06-3
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

Guidance literature:: 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃;

With sodium hydroxide; ethanol; water; dihydrogen peroxide; at 0 - 20 ℃; for 1h;

Reference yield: 80.0%

: 64-17-5
ethanol

: 1032281-02-9
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

: 1032281-06-3
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6α-hydroxymethylmorphinan

Guidance literature:: 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃;

ethanol; With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 1h;