17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

Base Information

Chemical Name:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan
CAS No.:1032281-02-9
Molecular Formula:C₂₈H₃₁NO₃
Molecular Weight:429.559
Hs Code.:

Synonyms:17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

Suppliers and Price of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

Chemical Property:

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Technology Process of 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

There total 3 articles about 17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 100-39-0
benzyl bromide

: 58895-64-0
nalmefene hydrochloride

: 1032281-02-9
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 16590-41-3
Naltrexone

: 1779-49-3
Methyltriphenylphosphonium bromide

: 100-39-0
benzyl bromide

: 1032281-02-9
17-cyclopropylmethyl-4,5α-epoxy-3-benzyloxy-14-hydroxy-6-methylene-morphinan

Guidance literature:: Naltrexone; benzyl bromide; With potassium carbonate; In N,N-dimethyl-formamide;

Methyltriphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran;
DOI:10.1186/s12929-021-00758-y