2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Base Information

Chemical Name:2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile
CAS No.:1610369-82-8
Molecular Formula:C₁₄H₁₂N₄O₂
Molecular Weight:268.275
Hs Code.:

Synonyms:2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Suppliers and Price of 2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

There total 3 articles about 2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1610369-80-6
5-(cyanomethyl)-1-(4-methoxyphenyl)-N-(2-oxoethyl)-4,5-dihydro-1H-pyrazole-3-carboxamide

: 1610369-82-8
2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; triphenylphosphine / acetonitrile / 0 - 20 °C

2: boron dimethyl-trifluoro sulphide / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With boron dimethyl-trifluoro sulphide; triethylamine; triphenylphosphine; In dichloromethane; acetonitrile;

Reference yield:

: 1610369-79-3
methyl 5-(cyanomethyl)-1-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-carboxylate

: 1610369-82-8
2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: methanol / 48 h / 50 °C

2: hydrogenchloride; water / tetrahydrofuran / 60 h / 20 °C

3: triethylamine; triphenylphosphine / acetonitrile / 0 - 20 °C

4: boron dimethyl-trifluoro sulphide / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; boron dimethyl-trifluoro sulphide; water; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;

Reference yield:

: 1610369-78-2
5-(cyanomethyl)-N-(2,2-dimethoxyethyl)-1-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide

: 1610369-82-8
2-(1-(4-hydroxyphenyl)-3-(oxazol-2-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; water / tetrahydrofuran / 60 h / 20 °C

2: triethylamine; triphenylphosphine / acetonitrile / 0 - 20 °C

3: boron dimethyl-trifluoro sulphide / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; boron dimethyl-trifluoro sulphide; water; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; acetonitrile;