N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline
CAS No.:92686-80-1
Molecular Formula:C₂₂H₃₀N₂OSi
Molecular Weight:366.578
Hs Code.:

Synonyms:N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Suppliers and Price of N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

There total 3 articles about N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.5%

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: N,N-Dimethyl-N'-((1S,2S)-1-methyl-2-phenyl-2-trimethylsilanyloxy-ethyl)-formamidine

: 92686-80-1
N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Guidance literature:: ammonium sulfate; In toluene; for 10h; Heating;
DOI:10.1016/S0040-4020(01)82421-2

Reference yield:

: 2153-98-2
(-)-Norpseudoephedrine hydrochloride

: 92686-80-1
N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 91.1 percent / Et₃N / CH₂Cl₂

2: 40 °C

3: 86.5 percent / (NH₄)2SO₄ / toluene / 10 h / Heating

With triethylamine; ammonium sulfate; In dichloromethane; toluene;
DOI:10.1016/S0040-4020(01)82421-2

Reference yield:

: 92686-71-0
(1S,2S)-1-phenyl-1-trimethylsilyloxy-2-amino-propane

: 92686-80-1
N'-(1S,2S)-1-phenyl-1-trimethylsilyloxy-3-metoxymethyl-2-amino propane 1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 40 °C

2: 86.5 percent / (NH₄)2SO₄ / toluene / 10 h / Heating

ammonium sulfate; In toluene;
DOI:10.1016/S0040-4020(01)82421-2