ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate

Base Information

• Chemical Name: ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate
• CAS No.: 140157-68-2
• Molecular Formula: C₂₃H₂₄BrNO₄
• Molecular Weight: 458.352

Synonyms:ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate

Chemical Property of ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate

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Technology Process of ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate

There total 2 articles about ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

copper(I) oxide (1317-39-1,146060-06-2) + 4-<2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy>aniline (103788-87-0) + ethyl acrylate (140-88-5,9003-32-1) → ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate (140157-68-2) + 3-[4-(2-(5-Methyl-2-phenyl-4-oxazolyl)-phenyl]-2-methylthio-2-propanoic Acid

Guidance literature:

With hydrogen bromide; sodium nitrite; In water; acetone;

Reference yield:

copper(I) oxide (1317-39-1,146060-06-2) + 4-<2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy>aniline (103788-87-0) + ethyl acrylate (140-88-5,9003-32-1) → 3-[4-(2-(5-Methyl-2-phenyl-4-oxazolyl)-phenyl]-2-(methylthio)propanoic Acid + ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate (140157-68-2)

Guidance literature:

With hydrogen bromide; sodium nitrite; In water; acetone;

Reference yield:

ethyl alpha-bromo-4-[ 2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzenepropanoate (140157-68-2) + tiolacetic acid (507-09-5) → Ethyl 3-[4-(2-(5-Methyl-2-phenyl-4-oxazolyl)-ethoxy)phenyl]-2-(acetylthio)propanoate (140129-26-6)

Guidance literature:

With potassium carbonate; In N-methyl-acetamide;

upstream raw materials:

copper(I) oxide

4-<2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy>aniline

ethyl acrylate

Downstream raw materials:

Ethyl 3-[4-(2-(5-Methyl-2-phenyl-4-oxazolyl)-ethoxy)phenyl]-2-(acetylthio)propanoate

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