(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

Base Information

Chemical Name:(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate
CAS No.:853056-99-2
Molecular Formula:C₂₈H₄₁NO₃
Molecular Weight:439.638
Hs Code.:

Synonyms:(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

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Chemical Property of (2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

Chemical Property:

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Technology Process of (2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

There total 4 articles about (2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 853056-98-1
(R)-2-(4-octylphenyl)-1-((S)-1-((R)-1-phenylethyl)aziridin-2-yl)ethanol

: 64-19-7,77671-22-8
acetic acid

: 853056-99-2
(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

Guidance literature:: In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmc.2005.02.053

Reference yield:

: 853056-97-0
2-(4-octylphenyl)-1-((S)-1-((R)-1-phenylethyl)aziridin-2-yl)ethanone

: 853056-99-2
(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminum hydride / tetrahydrofuran / 1 h / 0 °C

2: 90 percent / CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2005.02.053

Reference yield:

: 853056-96-9
N-[(R)-α-methylbenzyl]-(2S)-aziridine-(N'-methoxy-N'-methyl)carboxamide

: 853056-99-2
(2S,3R)-2-((R)-1-phenylethylamino)-3-hydroxy-4-(4-octylphenyl)butyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / Mg / tetrahydrofuran / 20 - 50 °C

2: lithium aluminum hydride / tetrahydrofuran / 1 h / 0 °C

3: 90 percent / CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; magnesium; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2005.02.053