(3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol

Base Information

• Chemical Name: (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol
• CAS No.: 191939-01-2
• Molecular Formula: C₃₀H₄₉IO₂Si
• Molecular Weight: 596.708
• Mol file: 191939-01-2.mol

Synonyms:(3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol

Chemical Property of (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol

There total 2 articles about (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Triethylsilyl-3-furaldehyde (130493-22-0) → (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol (191939-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / diethyl ether

In diethyl ether;

DOI:10.1039/a701936j

Reference yield:

(RS)-1-(5-triethylsilylfuran-3-yl)-but-3-yn-1-ol (191938-99-5) → (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol (191939-01-2)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1039/a701936j

Reference yield: 94.0%

carbon monoxide (201230-82-2) + (3Z,7E)-4-Iodo-8-methyl-1-(5-triethylsilanyl-furan-3-yl)-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,7-dien-1-ol (191939-01-2) → 3-[(E)-4-Methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hex-3-enyl]-6-(5-triethylsilanyl-furan-3-yl)-5,6-dihydro-pyran-2-one (191939-02-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; methanol; at 60 ℃; for 24h; under 1520 Torr;

DOI:10.1039/a701936j

upstream raw materials:

(RS)-1-(5-triethylsilylfuran-3-yl)-but-3-yn-1-ol

5-Triethylsilyl-3-furaldehyde

Downstream raw materials:

3-[(E)-4-Methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hex-3-enyl]-6-(5-triethylsilanyl-furan-3-yl)-5,6-dihydro-pyran-2-one

5-Hydroxy-4-{6-hydroxy-5-[(E)-4-methyl-6-(2,6,6-trimethyl-cyclohex-1-enyl)-hex-3-enyl]-3,6-dihydro-2H-pyran-2-yl}-5H-furan-2-one