N-Chlorosuccinimide

Base Information Edit

Chemical Name:N-Chlorosuccinimide
CAS No.:128-09-6
Deprecated CAS:952714-33-9
Molecular Formula:C4H4ClNO2
Molecular Weight:133.534
Hs Code.:29251995
European Community (EC) Number:204-878-8
NSC Number:8748
UNII:0FWP306H7X
DSSTox Substance ID:DTXSID2042199
Nikkaji Number:J5.406B
Wikipedia:N-Chlorosuccinimide
Wikidata:Q286192
Metabolomics Workbench ID:58586
ChEMBL ID:CHEMBL2107513
Mol file:128-09-6.mol

Synonyms:N-chlorosuccinimide

Suppliers and Price of N-Chlorosuccinimide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Chlorosuccinimide
250g
$ 155.00

TCI Chemical
N-Chlorosuccinimide >98.0%(T)
100g
$ 20.00

TCI Chemical
N-Chlorosuccinimide >98.0%(T)
25g
$ 13.00

TCI Chemical
N-Chlorosuccinimide >98.0%(T)
500g
$ 54.00

SynQuest Laboratories
N-Chlorosuccinimide 99%
1 kg
$ 100.00

SynQuest Laboratories
N-Chlorosuccinimide 99%
500 g
$ 55.00

Sigma-Aldrich
N-Chlorosuccinimide N-Chlorosuccinimide Msynth?plus. CAS 128-09-6, pH (20?g/l, H?O)?acidic.
8450271000
$ 231.00

Sigma-Aldrich
N-Chlorosuccinimide Msynth?plus
1 kg
$ 221.07

Sigma-Aldrich
N-Chlorosuccinimide for synthesis. CAS 128-09-6, pH (20 g/l, H O) acidic., for synthesis
8028110250
$ 68.30

Sigma-Aldrich
N-Chlorosuccinimide for synthesis
250 g
$ 65.40

Total 190 raw suppliers

Chemical Property of N-Chlorosuccinimide Edit

Chemical Property:

Appearance/Colour:white to off-white crystalline powder
Vapor Pressure:0.323mmHg at 25°C
Melting Point:144-148 °C
Refractive Index:1.532
Boiling Point:200.5 °C at 760 mmHg
PKA:-2.78±0.20(Predicted)
Flash Point:75.1 °C
PSA：37.38000
Density:1.5 g/cm³
LogP:0.22710
Storage Temp.:Store at +2°C to +8°C.
Sensitive.:Moisture Sensitive
Solubility.:14g/l
Water Solubility.:Soluble in water, alcohol, benzene, acetone and acetic acid. Slightly soluble in ether, chloroform, carbon tetrachloride and pet
XLogP3:-0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:132.9930561
Heavy Atom Count:8
Complexity:129

Purity/Quality:

98%99% ^*data from raw suppliers

N-Chlorosuccinimide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,C
Hazard Codes:C,Xi
Statements: 22-34
Safety Statements: 26-36/37/39-45-37/39

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Succinimides
Canonical SMILES:C1CC(=O)N(C1=O)Cl
Uses N-Chlorosuccinimide is a chlorinating agent for the side-chain halogenation of alkylarenes. It is used frequently for the side-chain chlorination of sensitive hetarenes. N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high regioselectivity.N-Chlorosuccinimide is used as a chlorinating agent, mild oxidant and swimming pool disinfectant. It is used in the microdetermination of hydrazine salts by titrimetry as well as in the detection of arsenic in the +3 oxidative state. It is also employed in the production of rubber additives. Further, it is used as pharmaceutical intermediate and antibiotic drugs intermediate.

Technology Process of N-Chlorosuccinimide

There total 13 articles about N-Chlorosuccinimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%