5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde

Base Information

• Chemical Name: 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde
• CAS No.: 1264371-42-7
• Molecular Formula: C₃₂H₃₈O₆
• Molecular Weight: 518.65
• Mol file: 1264371-42-7.mol

Synonyms:5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde

Chemical Property of 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde

There total 3 articles about 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,3-dimethanol benzene (626-18-6) + 3-tert-butyl-5-(chloromethyl)-2-hydroxybenzaldehyde (183017-88-1) → 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde (1264371-42-7)

Guidance literature:

1,3-dimethanol benzene; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

3-tert-butyl-5-(chloromethyl)-2-hydroxybenzaldehyde; In tetrahydrofuran; mineral oil; at 25 - 30 ℃; Inert atmosphere;

DOI:10.1002/adsc.201700788

Reference yield:

2-tert-Butylphenol (88-18-6) → 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde (1264371-42-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 2,6-dimethylpyridine; tin(IV) chloride / toluene / 8 h / Reflux

2.1: hydrogenchloride / water / 48 h / 45 - 50 °C

3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 20 °C / Inert atmosphere

3.2: 25 - 30 °C / Inert atmosphere

With 2,6-dimethylpyridine; hydrogenchloride; tin(IV) chloride; sodium hydride; In tetrahydrofuran; water; toluene; mineral oil;

DOI:10.1002/adsc.201700788

Reference yield:

3-tert-butyl-2-hydroxybenzaldehyde (24623-65-2) → 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde (1264371-42-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride / water / 48 h / 45 - 50 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 20 °C / Inert atmosphere

2.2: 25 - 30 °C / Inert atmosphere

With hydrogenchloride; sodium hydride; In tetrahydrofuran; water; mineral oil;

DOI:10.1002/adsc.201700788

upstream raw materials:

1,3-dimethanol benzene

3-tert-butyl-5-(chloromethyl)-2-hydroxybenzaldehyde

2-tert-Butylphenol

3-tert-butyl-2-hydroxybenzaldehyde