183017-88-1

Basic information

• Product Name: Benzaldehyde, 5-(chloromethyl)-3-(1,1-dimethylethyl)-2-hydroxy-
• CAS NO: 183017-88-1
• Molecular Formula: C12H15ClO2
• Molecular Weight: 226.703
• Mol File: 183017-88-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 5-(chloromethyl)-3-(1,1-dimethylethyl)-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 5-(chloromethyl)-3-(1,1-dimethylethyl)-2-hydroxy-(183017-88-1)
• EPA Substance Registry System: Benzaldehyde, 5-(chloromethyl)-3-(1,1-dimethylethyl)-2-hydroxy-(183017-88-1)

Safety Data

• Hazardous Substances Data: 183017-88-1(Hazardous Substances Data)

Upstream product

• 88-18-6 2-tert-Butylphenol 
• 110-88-3 1,3,5-Trioxan 
• 24623-65-2 3-tert-butyl-2-hydroxybenzaldehyde 

Downstream Products

• 188999-64-6 3-t-butyl-5-(trimethylammoniomethyl)salicylaldehyde chloride 
• 1030871-49-8 C₁₈H₂₇ClN₂O 
• 446023-31-0 C₃₃H₄₇ClN₂O₂ 
• 1264371-42-7 5,5’-(((1,3-phenylenebis(methylene))-bis(oxy))bis(methylene))bis(3-tert-butyl)-2-hydroxybenzaldehyde 
• 1384631-95-1 (R,R)-N-(3,5-di-tert-butylsalicylidene)-N′-(3-tert-butyl-5-chloromethyl-salicylidene)-1,2-cyclohexanediamine 
• 1350430-29-3 Br^(1-)*C₇₅H₁₁₁N₈O₄⁽¹⁺⁾ 
• 1438999-84-8 3-(tert-butyl)-2-hydroxy-5-(((10-hydroxydecyl)oxy)methyl)benzaldehyde 
• 1160297-39-1 (R,R)-{N-(3-tert-butyl-5-chloromethyl-salicylidine)-N'-(3'-tert-butyl-5'-chloromethyl-salicylidine)}-1,2-cyclohexanediamine 
• 886055-55-6 3-tert-butyl-2-hydroxy-5-(2'-hydroxyethoxymethyl)benzaldehyde 

Relevant articles and documents

Synthesis and characterization of bulky salen-type complexes of Co, Cu, Fe, Mn and Ni with amphiphilic solubility properties

Several new bulky salen-type Schiff base ligands and their complexes with first-row transition metals Co, Cu, Fe, Mn and Ni have been synthesized and characterized. The ligands contain tert-butyl and methyl(triphenylphosphonium chloride) substituents in aromatic rings providing flexible solubility properties. Crystal structures of some of the complexes were determined.

Asymmetric aerobic oxidation of α-hydroxy acid derivatives catalyzed by reusable, polystyrene-supported chiral N-salicylidene oxidovanadium tert-leucinates

The direct immobilization of two different C-5-propargyl ether-modified, chiral N-salicylidene vanadyl(V) tert-leucinates onto 4-azidomethyl-substituted polystyrene by click chemistry was examined. Among the eight different solvents investigated, the resulting polystyrene-supported catalysts promote the asymmetric, aerobic oxidation of α-hydroxy (thio)esters and amides with enantioselectivities of up to 99% ee (selectivity factor up to 41) in chloroform. These polystyrene-supported catalysts can be readily recovered by filtration and reused for at least four consecutive runs without discernible loss of reactivity and enantioselectivity.

Polyglycerol-supported chromium-salen as a high-loading dendritic catalyst for stereoselective Diels-Alder reactions

In this paper we demonstrate the application of hyperbranched polyglycerol (PG) 3 as a polymeric support for asymmetric catalysis. A new polyglycerol-supported unsymmetrical salen ligand 4 is described, which was successfully purified by gel permeation chromatography (GPC) or by ultrafiltration. After the insertion of the metal, e.g., chromium, the corresponding polymeric chromium complex was used as catalyst for asymmetric Diels-Alder reactions between Danishefsky's diene and benzaldehyde. The catalytic activities (up to 98% conversion) and enantioselectivities (up to 78% ee) were comparable to the original catalyst reported by Jacobsen. The soluble polyglycerol-supported catalysts were recovered by dialysis after the catalytic reactions and were recycled two times to afford identical reactivities as in the first run, with slightly reduced enantioselectivities. Moreover, this polymeric support catalyst showed a high retention (99.02%) in a continuously operated membrane reactor.