1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane

Base Information

• Chemical Name: 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane
• CAS No.: 146462-59-1
• Molecular Formula: C₂₆H₃₀O₆S
• Molecular Weight: 470.587
• Mol file: 146462-59-1.mol

Synonyms:1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane

Chemical Property of 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane

There total 6 articles about 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

10,10,10-triphenyl-3,6,9-trioxadecan-1-ol (133699-09-9) + methanesulfonyl chloride (124-63-0) → 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane (146462-59-1)

Guidance literature:

With triethylamine; In dichloromethane; for 1.16667h; Cooling with ice;

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane (146462-59-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / pyridine / 24 h / 45 °C

2: 60 percent / pyridine / 24 h / 4 °C

In pyridine;

DOI:10.1016/j.bmcl.2006.01.003

Reference yield:

trityl chloride (76-83-5) → 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane (146462-59-1)

Guidance literature:

Multi-step reaction with 2 steps

1: DMAP; Et₃N / CH₂Cl₂ / 20 °C

2: 13.2 g / Et₃N / CH₂Cl₂ / 12 h / 0 - 20 °C

With dmap; triethylamine; In dichloromethane; 1: tritylation / 2: mesylation;

DOI:10.1021/ja964099e

upstream raw materials:

10,10,10-triphenyl-3,6,9-trioxadecan-1-ol

methanesulfonyl chloride

trityl chloride

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Downstream raw materials:

(2R,3R,4S,5S,6R)-3,4,5-Tris-benzyloxy-2-ethylsulfanyl-6-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxymethyl}-tetrahydro-pyran

[{2-[2-(2-azidoethoxy)ethoxy]ethoxy}(diphenyl)methyl]benzene

19-(triphenylmethyl)-1,4,7,10,13,16,19-heptaoxanonadecanol

C₅₁H₅₅N₃O₇