(2R)-5-amino-2-azaniumyl-5-oxopentanoate

Base Information

Chemical Name:(2R)-5-amino-2-azaniumyl-5-oxopentanoate
CAS No.:5959-95-5
Molecular Formula:C5H10N2O3
Molecular Weight:146.146
Hs Code.:29241900
Mol file:5959-95-5.mol

Synonyms:glutamide;D-glutamine zwitterion;CHEBI:58000;(2R)-5-amino-2-azaniumyl-5-oxopentanoate

Suppliers and Price of (2R)-5-amino-2-azaniumyl-5-oxopentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-Glutamine
5g
$ 373.00

Usbiological
D-Glutamine, 99+%
5g
$ 192.00

TRC
D-Glutamine
10g
$ 545.00

TCI Chemical
D-Glutamine >98.0%(T)
1g
$ 29.00

TCI Chemical
D-Glutamine >98.0%(T)
5g
$ 133.00

Sigma-Aldrich
D-Glutamine ≥98% (HPLC)
10g
$ 570.00

Sigma-Aldrich
D-Glutamine ≥98% (HPLC)
1g
$ 95.10

Sigma-Aldrich
D-Glutamine ≥98% (HPLC)
5g
$ 379.00

Labseeker
(R)-2-AMINO-4-CARBAMOYL-BUTYRIC ACID 95
100g
$ 431.00

Labseeker
(R)-2-AMINO-4-CARBAMOYL-BUTYRIC ACID 95
500g
$ 769.00

Total 145 raw suppliers

Chemical Property of (2R)-5-amino-2-azaniumyl-5-oxopentanoate

Chemical Property:

Appearance/Colour:white crystalline powder
Melting Point:184-185 °C
Refractive Index:-33 ° (C=5, 5mol/L HCl)
Boiling Point:445.6 °C at 760 mmHg
PKA:2.27±0.10(Predicted)
Flash Point:223.3 °C
PSA：106.41000
Density:1.321 g/cm³
LogP:0.06440
Storage Temp.:-15°C
Solubility.:Water (Slightly, Sonicated)
Water Solubility.:42.53g/L(temperature not stated)
XLogP3:-2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:146.06914219
Heavy Atom Count:10
Complexity:140

Purity/Quality:

min98% ^*data from raw suppliers

D-Glutamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 36/37/39-26-27-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)N)C(C(=O)[O-])[NH3+]
Isomeric SMILES:C(CC(=O)N)[C@H](C(=O)[O-])[NH3+]
Uses D-Glutamine is an unnatural isomer of L-Glutamine (G597000) that is present in human plasma an is a source of liberated ammonia. D-Glutamine can be synthesized by enzymatic means or can be found in cheeses, wine and vinegars as well. It is often used to determine the activity of Glutamine synthetase, an enzyme that is commonly found in the mammalian liver and brain that controls the use of nitrogen in cells. D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer.

Technology Process of (2R)-5-amino-2-azaniumyl-5-oxopentanoate

There total 28 articles about (2R)-5-amino-2-azaniumyl-5-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 7607-72-9,2110-19-2,174591-46-9
2-phthalimidoglutaramic acid

: 56-85-9,585-21-7,5959-95-5,6899-04-3,26700-71-0
GLUTAMINE

Guidance literature:: With hydrazine hydrate; In water; at 20 ℃; for 48h;
DOI:10.1016/j.molstruc.2020.128600

Reference yield:

: 56-85-9,585-21-7,5959-95-5,6899-04-3,26700-71-0
GLUTAMINE

: 617-65-2,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
Glutamic acid

Guidance literature:

Reference yield:

: 6349-98-0,2301-52-2
N-phthalylglutamic acid

: 56-85-9,585-21-7,5959-95-5,6899-04-3,26700-71-0
GLUTAMINE

Guidance literature:: Multi-step reaction with 3 steps

1: acetic anhydride / 0.25 h / Reflux

2: ammonia / 0.33 h / 20 °C

3: hydrazine hydrate / water / 48 h / 20 °C

With ammonia; acetic anhydride; hydrazine hydrate; In water;
DOI:10.1016/j.molstruc.2020.128600