Lipase

Base Information

• Chemical Name: Lipase
• CAS No.: 9001-62-1
• Molecular Formula: Unspecified
• Molecular Weight: 238.19783
• Hs Code.: 35079020
• Mol file: 9001-62-1.mol

Synonyms:ABSFungal Lipase L;Lipase PF;Lipase PL 266;Lipase PLG;Lipase PN;Lipase PS;Lipase PS Amano SD;Acid lipase;Adipose triglyceride lipase;Alfamalt LP 10066;Allzyme Lipase;Altus 13;Altus 2;Amano AP;Amano AY 1;Amano B;Amano CE;Amano CES;Amano I;Amano II;Amano LPL 200S;Amano M;Amano N-AP;Amano P;Amano PS 30;Arthrobacter lipase;Bakezyme PH 800;Bile salt-activated lipase;Bioprase OP 10;Butyrinase;Buzyme 2517;Cacordase;Capalase;Capalase K;Capalase L;Cartazyme LP;Chirazyme 435;Chirazyme L;Chirazyme L 1;Chirazyme L 10;Chirazyme L 2;Chirazyme L2C2;Chirazyme L 3;Chirazyme L 5;Chirazyme L 6;Chirazyme L 7;Chirazyme L 8;Chirazyme L 9;Chirazyme c-f;ChiroCLEC-CAB;ChiroCLEC-CR;ChiroCLEC-PC;Cleanase NLA-P;CloneZyme ESL 001;E.C.3.1.1.3;Enzylon PF;Fetipase;Fluozim G 3Kh;GA 56;GA 56(enzyme);Glycerol ester hydrolase;Greasex;Greasex 100L;ICR-107;ICR-113;Italase;Italase C;Lilipase A 10;Lilipase A 10FG;Lilipase A 5;Lilipase B 2;Lillipase A-10FG;Lipase;Lipase A;Lipase A 100L;Lipase A 10FG;Lipase AH;Lipase AK Amano;Lipase AKG;Lipase ALC;Lipase ALG;Lipase AP;Lipase AS;Lipase AY;Lipase AY 30;Lipase AY Amano 6;Lipase CE;Lipase CR;Lipase D Amano 2000;Lipase D Amano 350;Lipase EU-034;Lipase GC Amano 4;Lipase L Amano 10;Lipase LAK;Lipase LP;Lipase LP 'S';Lipase M 10;Lipase M-AP 10;Lipase MY;Lipase OF;Lipase OFEX;Lipase PA;

Chemical Property of Lipase

Chemical Property:

• Appearance/Colour: yellow-brown solution
• Vapor Pressure: 0.004Pa at 25℃
• Density: 1.2
• Storage Temp.: 2-8°C
• Solubility.: H2O: 2 mg/mL, hazy with insoluble particles, faintly yellow
• Water Solubility.: It is soluble in water.

Purity/Quality:

99%min ^*data from raw suppliers

Novozym(R) 51032 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): B,Xn
• Hazard Codes: B,Xn
• Statements: 20/21/22
• Safety Statements: 22-24/25-36/37-36

MSDS Files:

SDS file from LookChem

Useful:

• Description: Lipase is an enzyme and belongs to the class of hydrolase. Lipase is produced in the pancreas, mouth, and stomach.? It catalyzes the hydrolysis of triglycerides to glycerol and free fatty acids. The body uses lipase to break down fats in food so they can be absorbed in the intestines. Lipases are widely employed to catalyze hydrolysis, alcoholysis, esterification, interesterification, acidolysis and transesterification of carboxylic esters. Their unique characteristics include substrate specificity, stereospecificity, regioselectivity and ability to catalyze a heterogeneous reaction at the interface of water soluble and water insoluble systems. Lipases are used as flavor and aroma constituents in the food industry, to produce valuable oleo chemical species for diesel engines,? as additives in cosmetic formulations, to remove the pitch from pulp produced in the paper industry, for the hydrolysis of milk fat in the dairy industry, to remove non-cellulosic impurities from raw cotton before further processing into dyed and finished products, for the drug formulations in the pharmaceutical industry, and to remove subcutaneous fat in the leather industry. Lipases are also used to diagnose pancreatitis in patients. Clinically lipases help a person who has cystic fibrosis, Alzheimer's disease, atherosclerosis and act as a candidate target for cancer prevention and therapy. Lipases are also used to treat obesity in recent years. Lipase is obtained from two primary sources: (1) the edible fore stomach tissue of calves, kids, or lambs and; (2 ) animal pancreatic tissue. It is produced as purified edible tissue preparations or as aqueous extracts. It is dispersible in water and insoluble in alcohol. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Produced by the controlled fermentation of Aspergillus niger var. as an off-white to tan amorphous powder. Soluble in water (the solution is usually light yellow), but practically insoluble in alco hol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Produced by the controlled fermentation of Aspergillus oryzae var. as an off-white to tan amorphous powder or a liquid. Soluble in water (the solution is usually light yellow), but practically insol uble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Produced by the controlled fermentation of Candida rugosa as an off-white to tan powder. Soluble in water but practically insoluble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1.
• Uses: To split fats without damaging sensitive constituents, such as vitamins or unsaturated fatty acids. In food processing for flavor improvement; in detergents for the improvement of cleaning action. For review of industrial applications of microbial lipases, see Seitz, J. Am. Oil Chem. Soc. 51, 12 (1974). Trans fatty acids (TFAs) are fatty acids with at least one double bond in (E)- configuration. The consumption of TFAs increases the risk of coronary heart diseases. Thus, their concentrations in lipid-containing products should be reduced [87]. Naturally, TFAs occur in small amounts in meat and milk of ruminants, but the most significant concentrations of TFAs develop during partial hydrogenation and deodorization of fats [88]. The formation of TFAs during fat hardening can be avoided by lipase catalyzed transesterification to increase the slip melting points of fats. For enzymatic transesterification between different lipids, triacylglycerol lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) acting on the SN1 and SN3 positions of the triglyceride are used. Various lipases have been applied for the production of table margarine out of fat-oil blends. Lipases of the ascomycetes Thermomyces lanuginosa and Rhizomucor miehei, as well as a lipase of the proteobacterium Pseudomonas sp., were used for transesterification of fat blends consisting of palm stearin and vegetable oil. Fully hydrogenated oils in blends with vegetable oils also have been used. In all studies, an increase of the slip melting points and the solid fat content was achieved in the fat-oil blend, thus indicating an alternative method for fat hardening via hydrogenation. Lipase, is used as a catalyst in the preparation of biodiesels?and in the preparation of esters of chiral epoxy alcohols.?Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel.

Technology Process of Lipase

There total 2 articles about Lipase which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ (S)-(-)-2,3-dihydro-3-(4'-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol + lipase (9001-62-1)

Guidance literature:

Reference yield: 73.5%

→ (S)-decan-2-ol (33758-16-6) + lipase (9001-62-1)

Guidance literature:

Reference yield:

1-hexadecylcarboxylic acid (57-10-3) + lipase (9001-62-1) + hexan-1-ol (111-27-3) → isooctyl palmitate (106-05-8)

Guidance literature:

Downstream raw materials:

isooctyl palmitate

Refernces

• 1、 -. "Optical resolution for producing optically active alcohol". . . Retrieved 2008/06/13.