(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Base Information

Chemical Name:(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester
CAS No.:915106-62-6
Molecular Formula:C₄₆H₇₈O₇Si₃
Molecular Weight:827.378
Hs Code.:

(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Synonyms:(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Suppliers and Price of (3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

There total 1 articles about (3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 915106-52-4
(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid

: 107-18-6
allyl alcohol

: 915106-62-6
(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Guidance literature:: With dmap; diisopropyl-carbodiimide; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/ol0620904

Reference yield: 95.0%

: 915106-62-6
(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

: 915106-53-5
(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-3-carboxy-propyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite; phosphate buffer; In acetonitrile; at 50 ℃; for 1h; pH=7;
DOI:10.1021/ol0620904

Reference yield:

: 915106-62-6
(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-{(2R,6S)-6-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-butyl]-tetrahydro-pyran-2-yl}-hexanoic acid allyl ester

: C₇₇H₁₂₈O₁₆Si₄

Guidance literature:: Multi-step reaction with 2 steps

1.1: 95 percent / TEMPO; NaClO; NaClO₂ / phosphate buffer / acetonitrile / 1 h / 50 °C / pH 7

2.1: Et₃N; 2,4,6-trichlorobenzoyl chloride / toluene / 3 h / 20 °C

2.2: 72 percent / Et₃N; DMAP / toluene / 1 h / 20 °C

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite; 2,4,6-trichlorobenzoyl chloride; triethylamine; phosphate buffer; In toluene; acetonitrile;
DOI:10.1021/ol0620904