6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

Base Information

• Chemical Name: 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine
• CAS No.: 1245200-31-0
• Molecular Formula: C₂₉H₄₄N₈O₄Si₂
• Molecular Weight: 624.891

Synonyms:6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

Chemical Property of 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

There total 1 articles about 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

6-N,N-dibenzoyl-[2'-O-(trifluormethanesulfonyl)-3',5'-bis-O-(tert-butyldimethylsilyl)-1-β-D-xylofuranosyl]adenine (1245200-29-6) → 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine (1245200-31-0)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.201001473

Reference yield: 86.0%

6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine (1245200-31-0) → N-(9-((2R,3R,4S,5R)-3-azido-4-(tert-butyldimethylsilyloxy)-5(hydroxymethyl) tetrahydro-furan-2-yl)-9H-purin-6-yl)benzamide (1242450-41-4)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; water; at 0 ℃; for 18h;

DOI:10.1002/anie.201001473

Reference yield:

6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine (1245200-31-0) → 2′-amino-N6-benzoyl-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine (1452385-16-8)

Guidance literature:

With hydrogen; In methanol; at 20 ℃; for 12h; under 760.051 Torr;

DOI:10.1039/c3ob41206g

upstream raw materials:

6-N,N-dibenzoyl-[2'-O-(trifluormethanesulfonyl)-3',5'-bis-O-(tert-butyldimethylsilyl)-1-β-D-xylofuranosyl]adenine

Downstream raw materials:

N-(9-((2R,3R,4S,5R)-3-azido-4-(tert-butyldimethylsilyloxy)-5(hydroxymethyl) tetrahydro-furan-2-yl)-9H-purin-6-yl)benzamide

2′-amino-N⁶-benzoyl-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

N⁶-benzoyl-3′,5′-bis-O-(tert-butyl-dimethylsilyl)-2′-(S)-methylcarbamate2′-deoxyadenosine

N⁶-benzoyl-3′-O-(tert-butyldimethylsilyl)-2′-(N-tert-butyloxycarbonyl-L-alanine)amido-3′-deoxyadenosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1245200-31-0 6-N-benzoyl-2′-azido-3′,5′-bis-O-(tert-butyldimethylsilyl)-2′-deoxyadenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send