Chemical Property of 2-Methoxy-5-methylaniline
Chemical Property:
- Appearance/Colour:brown to black crystalline chunks
- Vapor Pressure:0.0381mmHg at 25°C
- Melting Point:50-52 °C(lit.)
- Refractive Index:1.549
- Boiling Point:235.398 °C at 760 mmHg
- PKA:4.66±0.10(Predicted)
- Flash Point:102.068 °C
- PSA：35.25000
- Density:1.039 g/cm3
- LogP:2.16700
- Storage Temp.:Room Temperature, under inert atmosphere
- Solubility.:Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
- Water Solubility.:Slightly soluble in hot water.
- XLogP3:1.7
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:1
- Exact Mass:137.084063974
- Heavy Atom Count:10
- Complexity:105
- Purity/Quality:
-
99% *data from raw suppliers
p-Cresidine *data from reagent suppliers
Safty Information:
- Pictogram(s):
T， 
Xi
- Hazard Codes:T,Xi
- Statements:
45-22
- Safety Statements:
53-45
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Nitrogen Compounds -> Amines, Aromatic
- Canonical SMILES:CC1=CC(=C(C=C1)OC)N
- Inhalation Risk:No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
- Effects of Long Term Exposure:This substance is possibly carcinogenic to humans.
-
Uses
p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing. 2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase. p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides.
