10.1016/j.molstruc.2016.03.085
The study presents the synthesis and characterization of a novel monospirocyclic phosphazene derivative, 4',4',6',6'-tetrachloro-3-(2-methoxyethyl)-3H,4H-spiro-1,3,2-benzoxaza phosphinine-2,2'-[1,3,5,2,4,6]triazatriphosphinine (SP1). The compound was synthesized by reacting hexachlorocyclotriphosphazene (N3P3Cl6) with the N/O donor-type molecule 2-{[(2-methoxyethyl)amino]methyl}phenol. The synthesized SP1 was characterized using various analytical techniques, including elemental analyses, mass spectrometry (MS), Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR) spectroscopy, and single-crystal X-ray diffraction analysis. The purpose of these chemicals and techniques was to verify the structure and investigate the properties of the newly synthesized compound. The study also employed density functional theory (DFT) calculations using the B3LYP method with a 6-311++G(d,p) basis set to predict the electrophilic and nucleophilic attack centers in SP1, further understanding its reactivity and potential applications in areas such as biomaterials, protective coatings, drug delivery, and fire-resistant materials.
10.1016/j.poly.2011.03.028
The research investigates the stereogenic properties of cyclotriphosphazene derivatives with two different chiral centers. The purpose is to explore the geometric isomers and racemic forms of these compounds, which have potential applications in various fields due to their chirality. Key chemicals used include hexachlorocyclotriphosphazene (N3P3Cl6) and gem-disubstituted cyclotriphosphazene derivatives (N3P3Cl4X2, where X = Ph, PhS, PhNH), which were reacted with N-methyl-1,3-propanediamine and 3-amino-1-propanol to produce compounds with two different stereogenic phosphorus atoms. The geometric isomers were separated and characterized using techniques such as X-ray crystallography, 31P and 1H NMR spectroscopy, and chiral HPLC. The study confirmed that these compounds exist as cis and trans geometric isomers and as two different racemic isomers. The enantiomers of the racemic compounds were analyzed using a chiral solvating agent (CSA) and chiral HPLC methods developed for this study. The conclusions highlight the successful synthesis and characterization of these chiral cyclotriphosphazene compounds, providing insights into their stereogenic properties and potential uses in chiral chemistry.
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