4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

Base Information

Chemical Name:4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester
CAS No.:908250-28-2
Molecular Formula:C₂₇H₂₉F₃N₂O₄
Molecular Weight:502.533
Hs Code.:

Synonyms:4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

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Chemical Property of 4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

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Technology Process of 4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

There total 3 articles about 4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 908250-24-8
1-(4-hydroxy-3-methylphenyl)-3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propan-1-one

: 105-36-2
ethyl bromoacetate

: 908250-28-2
4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

Guidance literature:: With potassium carbonate; In butanone; at 0 - 20 ℃; for 2h;

Reference yield:

: 628330-62-1
{3-isopropyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl}methanol

: 908250-28-2
4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / benzene

2: hydrogenchloride; sodium hydrogencarbonate; acetic acid / tetrahydrofuran

3: ammonium chloride; potassium carbonate / butanone

With hydrogenchloride; thionyl chloride; ammonium chloride; sodium hydrogencarbonate; potassium carbonate; acetic acid; In tetrahydrofuran; butanone; benzene;

Reference yield:

: 500581-73-7
3-(4-benzyloxy-3-methyl-phenyl)-3-oxo-propionic acid ethyl ester

: 908250-28-2
4-[3-[3-isopropyl-1-(4-trifluoromethylphenyl)-1H-pyrazol-4-yl]propionyl]-2-methylphenoxyacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; sodium hydrogencarbonate; acetic acid / tetrahydrofuran

2: ammonium chloride; potassium carbonate / butanone

With hydrogenchloride; ammonium chloride; sodium hydrogencarbonate; potassium carbonate; acetic acid; In tetrahydrofuran; butanone;