C₄₂H₅₂N₄O₇

Base Information

• Chemical Name: C₄₂H₅₂N₄O₇
• CAS No.: 1613625-07-2
• Molecular Formula: C₄₂H₅₂N₄O₇
• Molecular Weight: 724.897
• Mol file: 1613625-07-2.mol

Synonyms:C₄₂H₅₂N₄O₇

Chemical Property of C₄₂H₅₂N₄O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₅₂N₄O₇

There total 20 articles about C₄₂H₅₂N₄O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-tert-butoxycarbonyl-3-aminopropanol (58885-58-8) → C42H52N4O7 (1613625-07-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Dess-Martin periodane / dichloromethane / 2 h / 0 - 20 °C

2.1: acetic acid; sodium cyanoborohydride / methanol / 19 h / 20 °C

3.1: sodium hydrogencarbonate / methanol; water / 0.17 h / 0 °C

3.2: 3 h / 0 - 20 °C

With sodium cyanoborohydride; sodium hydrogencarbonate; Dess-Martin periodane; acetic acid; In methanol; dichloromethane; water;

Reference yield:

C34H46N4O5 (1613625-06-1) + benzyl chloroformate (501-53-1,94274-21-2) → C42H52N4O7 (1613625-07-2)

Guidance literature:

C₃₄H₄₆N₄O₅; With sodium hydrogencarbonate; In methanol; water; at 0 ℃; for 0.166667h;

benzyl chloroformate; In methanol; water; at 0 - 20 ℃; for 3h;

Reference yield:

γ-(4-methoxy-1-naphthyl)butyric acid (10465-20-0) → C42H52N4O7 (1613625-07-2)

Guidance literature:

Multi-step reaction with 17 steps

1.1: n-butyllithium / tetrahydrofuran / 0.75 h / -78 °C

1.2: 3.5 h / 0 - 20 °C

2.1: potassium hexamethylsilazane / tetrahydrofuran / 0.5 h / -78 °C

2.2: -78 °C

2.3: 16 h / -78 - 27 °C

3.1: dihydrogen peroxide; lithium hydroxide / tetrahydrofuran; water / 3 h / 0 °C

4.1: hydrogen; palladium 10% on activated carbon / water / 3 h / 20 °C / 760.05 Torr

5.1: acetic acid; hydrogen bromide / 4 h / Reflux

6.1: acetyl chloride / 4 h / 0 °C / Reflux

7.1: sodium hydrogencarbonate / methanol; water / 3 h / 0 - 20 °C

8.1: pyridine / 2.5 h / 0 - 20 °C

9.1: tri-tert-butyl phosphine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / acetonitrile; hexane / 5 h / Inert atmosphere; Reflux

10.1: sodium hydroxide; water / tetrahydrofuran; methanol / 3 h / 20 °C

11.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / 0 °C

12.1: ammonia / methanol / 18 h / 0 - 20 °C

13.1: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 20 °C / 760.05 Torr

14.1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

15.1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 6 h / 20 °C

16.1: acetic acid; sodium cyanoborohydride / methanol / 19 h / 20 °C

17.1: sodium hydrogencarbonate / methanol; water / 0.17 h / 0 °C

17.2: 3 h / 0 - 20 °C

With 4-methyl-morpholine; pyridine; hydrogenchloride; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; tri-tert-butyl phosphine; palladium 10% on activated carbon; ammonia; water; hydrogen bromide; hydrogen; dihydrogen peroxide; potassium hexamethylsilazane; sodium cyanoborohydride; sodium hydrogencarbonate; acetic acid; triethylamine; acetyl chloride; sodium hydroxide; lithium hydroxide; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; hexane; dichloromethane; water; acetonitrile;

upstream raw materials:

N-tert-butoxycarbonyl-3-aminopropanol

C₃₄H₄₆N₄O₅

benzyl chloroformate

γ-(4-methoxy-1-naphthyl)butyric acid

Downstream raw materials:

C₃₇H₄₄N₄O₅