Ferric pyrophosphate

Base Information

• Chemical Name: Ferric pyrophosphate
• CAS No.: 10058-44-3
• Deprecated CAS: 87059-16-3,59938-19-1,65214-07-5
• Molecular Formula: Fe4^.(P2O7)3
• Molecular Weight: 745.218
• Hs Code.: 2835299000
• European Community (EC) Number: 233-190-0
• UNII: QK8899250F
• DSSTox Substance ID: DTXSID6047600
• Wikipedia: Iron(III) pyrophosphate,Iron(III)_pyrophosphate
• Wikidata: Q9207442
• NCI Thesaurus Code: C82284
• Mol file: 10058-44-3.mol

Synonyms:Actiferol Fe;ferric pyrophosphate;ferric pyrophosphate nonahydrate;JM-3100;Sunactive Fe

Chemical Property of Ferric pyrophosphate

Chemical Property:

• Appearance/Colour: yellowish white powder
• PSA: 155.23000
• LogP: 0.93870
• Storage Temp.: Store at RT.
• Solubility.: Water
• Water Solubility.: insoluble H2O, acetic acid; soluble mineral acids [MER06]
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 21
• Rotatable Bond Count: 0
• Exact Mass: 745.47552
• Heavy Atom Count: 31
• Complexity: 124

Purity/Quality:

≥96% ^*data from raw suppliers

Iron(III)PyrophosphateSolubleCrystals ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Metals -> Phosphates, Metallic Salts
• Canonical SMILES: [O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
• Recent ClinicalTrials: A Comparative Absorption Study of Various Iron Salts Supplements
• Recent EU Clinical Trials: Study of the use of Liposomal Iron in the treatment of iron deficiency anemia in pregnancy and puerperium
• Description: Iron, which is the chief constituent of Earth’s core, is the most abundant element in Earth as a whole (about 35 percent) . Ferric pyrophosphate is an iron replacement product, is a mixed-ligand iron complex in which iron (III) is bound to pyrophosphate and citrate. It is widely used to fortify cereal flours and infant cereals, dispersible ferric pyrophosphate is as well absorbed as ferrous sulfate in adults. pyrophosphate ions participate in the ion transfer processes. These ions, as chelating agents, would release iron from transferrin and form a ferric pyrophosphate complex, and that pyrophosphate alone has the ability to mediate iron exchange from transferring to ferritin. Ferric pyrophosphate citrate should only be added to the bicarbonate concentrate; do not add to acid concentrate mixtures. Ferric pyrophosphate citrate is not intended for use in patients receiving peritoneal dialysis; it has not been studied in patients receiving home hemodialysis.
• Uses: Iron(III) Pyrophosphate can be used as an iron supplement for people with iron deficiencies. Food and Feed additives/Food additives Ferric Pyrophosphate is a nutrient supplement, tan or yellowish white in color, prepared by reacting sodium pyrophosphate with ferric citrate. the ingredient may be used in infant formula. it is also termed iron (iii) pyrophosphate.

Technology Process of Ferric pyrophosphate

There total 14 articles about Ferric pyrophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iron(III) phosphite * 9 H2O → ferric pyrophosphate (10058-44-3) + iron(II) phosphate + phosphan (7803-51-2)

Guidance literature:

In neat (no solvent); calcination Fe2(HPO3)3*9H2O; generation of PH3 and formation of Fe4(P2O7)3 and Fe3(PO4)2 as residue;;

Reference yield:

Iron(III) nitrate nonahydrate + ammonium dihydrogen phosphate (10124-31-9,10361-65-6,7783-28-0) → ferric pyrophosphate (10058-44-3)

Guidance literature:

Iron(III) nitrate nonahydrate; ammonium dihydrogen phosphate; With malic acid;

In neat (no solvent, solid phase); at 850 ℃; for 5h; Calcination;

DOI:10.1039/d1cy01265g

Reference yield:

iron(III) chloride + sodium pyrophosphate (124-43-6) → ferric pyrophosphate (10058-44-3)

Guidance literature:

In water; pH=3; Product distribution / selectivity;

upstream raw materials:

sodium pyrophosphate

iron(III) phosphate

ammonium dihydrogen phosphate

phosphoric acid

Refernces

• 1、 Masquelier, Christian,Reale, Priscilla,Wurm, Calin,Morcrette, Mathieu,Dupont, Loic,Larcher, Dominique. "Hydrated iron phosphates FePO4·nH2O and Fe4(P2O7)3·n H2O as 3 V positive electrodes in rechargeable lithium batteries". . p. A1037-A1044. Retrieved 2002.
• 2、 Padhi,Nanjundaswamy,Masquelier,Okada,Goodenough. "Effect of structure on the Fe3+/Fe2+ redox couple in iron phosphates". . p. 1609 - 1613. Retrieved 1997.
• 3、 Alfonso, Belen F.,Blanco, Jesus A.,Fernandez-Diaz, M. Teresa,Trobajo, Camino,Khainakov, Sergei A.,Garcia, Jose R.. "On the crystal structure and thermal decomposition of ammonium-iron(III) bis(hydrogenphosphate)". . p. 1791 - 1796. Retrieved 2010.
• 4、 Zhang, Liying,Schlesinger, Mark E.,Brow, Richard K.. "Phase Equilibria in the Fe2O3-P2O 5 System". . p. 1605 - 1610. Retrieved 2011.
• 5、 Hara, Michikazu,Kamata, Keigo,Matsuda, Aoi,Tateno, Haruka. "Iron phosphate nanoparticle catalyst for direct oxidation of methane into formaldehyde: Effect of surface redox and acid-base properties". . p. 6987 - 6998. Retrieved 2021/11/13.