2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester
CAS No.:93181-96-5
Molecular Formula:C₂₀H₂₄ClN₃O₂
Molecular Weight:373.882
Hs Code.:

Synonyms:2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Suppliers and Price of 2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

There total 3 articles about 2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 3282-30-2
pivaloyl chloride

: 93181-81-8
Lodaxaprine

: 93181-96-5
2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; for 18h; Heating;
DOI:10.1021/jm00153a011

Reference yield:

: 5382-16-1
4-HYDROXYPIPERIDINE

: 93181-96-5
2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / butan-1-ol / 3 h / Heating

2: 75 percent / Et₃N / tetrahydrofuran / 18 h / Heating

With triethylamine; In tetrahydrofuran; butan-1-ol;
DOI:10.1021/jm00153a011

Reference yield:

: 66549-15-3
3-chloro-6-(2-chlorophenyl)pyridazine

: 93181-96-5
2,2-Dimethyl-propionic acid 1-[6-(2-chloro-phenyl)-pyridazin-3-yl]-piperidin-4-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / butan-1-ol / 3 h / Heating

2: 75 percent / Et₃N / tetrahydrofuran / 18 h / Heating

With triethylamine; In tetrahydrofuran; butan-1-ol;
DOI:10.1021/jm00153a011