(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Base Information

Chemical Name:(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid
CAS No.:1083175-04-5
Molecular Formula:C₃₀H₄₂N₄O₈
Molecular Weight:586.685
Hs Code.:

Synonyms:(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Suppliers and Price of (2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

There total 6 articles about (2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1083175-03-4
(2S)-2-amino-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]pentanoic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 1083175-04-5
(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Guidance literature:: (2S)-2-amino-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]pentanoic acid; di-tert-butyl dicarbonate; With potassium carbonate; In water; acetone; for 1h; pH=10;

In water; acetone; pH=12; Alkaline aqueous solution;

With hydrogenchloride; water; In diethyl ether; pH=2;

Reference yield: 81.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1393476-94-2
(2S)-2-amino-5-[bis(2-{[(benzyloxy)carbonyl] amino}ethyl)amino]pentanoic acid trifluoro acetate

: 1083175-04-5
(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Guidance literature:: With potassium carbonate; In water; acetone; for 1h; pH=10;

Reference yield:

: 24277-39-2
N-tert-butoxycarbonyl glutamic acid tert-butyl ester

: 1083175-04-5
(2S)-5-[bis(2-{[(benzyloxy)carbonyl]amino}ethyl)amino]-2-{[(tert-butoxy)carbonyl]amino} pentanoic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C

2.1: dmap; triethylamine / acetonitrile / 2 h / 20 °C

3.1: diisobutylaluminium hydride / diethyl ether; tetrahydrofuran / -78 °C / Inert atmosphere

4.1: acetic acid / dichloromethane / 1 h / 0 °C

4.2: 20 °C

5.1: hydrogenchloride / ethyl acetate / 0.5 h / 20 °C

7.1: potassium carbonate / water; acetone / 1 h / pH 10

With hydrogenchloride; dmap; diisobutylaluminium hydride; potassium carbonate; acetic acid; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile;