(E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate

Base Information

• Chemical Name: (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate
• CAS No.: 1243388-61-5
• Molecular Formula: C₃₀H₂₆N₂O₁₀
• Molecular Weight: 574.544
• Mol file: 1243388-61-5.mol

Synonyms:(E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate

Chemical Property of (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate

There total 2 articles about (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

furfural (98-01-1) + pyridyl[1,2-a](2-phenylimidazol)-3-ylidene chloride (937030-04-1) + dimethyl acetylenedicarboxylate (762-42-5) → (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate (1243388-61-5)

Guidance literature:

With sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at -20 ℃; for 8h; Inert atmosphere;

DOI:10.1021/jo1014933

Reference yield: 50.0%

furfural (98-01-1) + pyridyl[1,2-a](2-phenylimidazol)-3-ylidene chloride (937030-04-1) + dimethyl acetylenedicarboxylate (762-42-5) → (Z)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)allyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate (1243388-46-6) + (E)-dimethyl 4-(N-(2,3-dimethoxycarbonyl-1-(2-pyridyl)prop-1-enyl)-N-phenylamino)-5-(2-furyl)furan-2,3-dicarboxylate (1243388-61-5)

Guidance literature:

With sodium hydride; In dichloromethane; at -20 ℃; for 8h; Inert atmosphere;

DOI:10.1021/jo1014933

upstream raw materials:

furfural

pyridyl[1,2-a](2-phenylimidazol)-3-ylidene chloride

dimethyl acetylenedicarboxylate