1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Base Information

Chemical Name:1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester
CAS No.:1232886-46-2
Molecular Formula:C₃₈H₄₇NO₆
Molecular Weight:613.794
Hs Code.:

Synonyms:1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Suppliers and Price of 1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

There total 3 articles about 1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1232884-73-9
(E)-3-(3'-adamantan-1-yl-4'-hydroxybiphenyl-4-yl)acrylic acid tert-butyl ester

: 88950-64-5
1-<(tert-butyloxy)carbonylamino>cyclopropane-1-carboxylic acid

: 1232886-46-2
1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2012.01.042

Reference yield:

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 1232886-46-2
1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / 1 h / 110 °C / Neat (no solvent)

2: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; palladium diacetate; triethylamine; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; In N,N-dimethyl-formamide; 1: Heck reaction;
DOI:10.1016/j.bmc.2012.01.042

Reference yield:

: 496868-80-5
4-(4'-bromophenyl)-2-(adamantan-1-yl)phenol

: 1232886-46-2
1-tert-butoxycarbonyl aminocyclopropanecarboxylic acid 3-adamantan-1-yl-4'-(2-tert-butoxycarbonylvinyl)biphenyl-4-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / 1 h / 110 °C / Neat (no solvent)

2: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; palladium diacetate; triethylamine; N-ethyl-N,N-diisopropylamine; tris-(o-tolyl)phosphine; In N,N-dimethyl-formamide; 1: Heck reaction;
DOI:10.1016/j.bmc.2012.01.042