Tris(8-quinolyloxy) gallium

Base Information

• Chemical Name: Tris(8-quinolyloxy) gallium
• CAS No.: 14642-34-3
• Molecular Formula: C₂₇H₁₈GaN₃O₃
• Molecular Weight: 502.181
• UNII: R3G3HB38O4
• Nikkaji Number: J1.204.151I
• NCI Thesaurus Code: C165650
• Mol file: 14642-34-3.mol

Synonyms:Tris(8-quinolyloxy) gallium;R3G3HB38O4;Gallium, tris(8-quinolinolato)-;Tris(8-hydroxyquinolinato)gallium;NKP-2235;AP-002;IT-235;LX-001;gallium;quinolin-8-olate;UNII-R3G3HB38O4;KP46;NSC 158197;NSC-158197;Gallium, tris(8-quinolinolato-kappaN1,kappaO8)-;GALLIUM, TRIS(8-QUINOLINOLATO-.KAPPA.N1,.KAPPA.O8)-

Chemical Property of Tris(8-quinolyloxy) gallium

Chemical Property:

• Vapor Pressure: 0.000741mmHg at 25°C
• Melting Point: >400 °C
• Boiling Point: 273.3°Cat760mmHg
• Flash Point: 119.2°C
• PSA: 60.69000
• Density: g/cm³
• LogP: 3.73940
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 501.06039
• Heavy Atom Count: 34
• Complexity: 138

Purity/Quality:

99% ^*data from raw suppliers

Gallium8-Hydroxyquinolinate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Ga+3]
• Recent ClinicalTrials: Evaluation of AP-002 in Patients With Solid Tumors
• Uses: Gallium 8-hydroxyquinolinate (CAS# 14642-34-3) is an open-shell compound used as organometallic semiconductors. Gallium 8-hydroxyquinolinate is also used as an analytical standard for the determination of Ga in blood plasma.

Technology Process of Tris(8-quinolyloxy) gallium

There total 5 articles about Tris(8-quinolyloxy) gallium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

8-quinolinol (148-24-3,24804-14-6) + Gallium trichloride (13450-90-3) → tris(8-hydroxyquinoline) gallium (14642-34-3,136781-05-0,107984-00-9)

Guidance literature:

With ammonium hydroxide; In ethanol; byproducts: ammonium chloride; to the quinoline (85.17 mmol) in ethanol was added an ethanolic soln. of GaCl3 (28.39 mmol) dropwise; stirring at room temp. under N2 for 24 h;an excess of ammonium hydroxide was added dropwise; stirring for 1 h; the ppt. was vac. filtered and washed with water and ethanol; the product was dried under vac. and purified by vac. train sublimation;

DOI:10.1016/S0039-6028(00)00232-6

Reference yield:

8-quinolinol (148-24-3,24804-14-6) + gallium(III) nitrate hexahydrate → tris(8-hydroxyquinoline) gallium (14642-34-3,136781-05-0,107984-00-9)

Guidance literature:

With ammonium acetate; In water; Ga salt was mixed with the aq. solution of the ligand buffered with ammonium acetate in a 1:3 molar ratio; recrystn. from MeOH; differential scanning calorimetry, thermal gravimetric anal.;

DOI:10.1021/ja010120m

Reference yield:

8-quinolinol (148-24-3,24804-14-6) + gallium(III) nitrate octahydrate → tris(8-hydroxyquinoline) gallium (14642-34-3,136781-05-0,107984-00-9)

Guidance literature:

With ammonium hydroxide; In isopropyl alcohol; at 50 ℃; for 1h; pH=9;

DOI:10.1039/c7ce02092a

upstream raw materials:

8-quinolinol

gallium(III)

Gallium trichloride

Refernces

• 1、 Wagner, Claudia C.,González-Baró, Ana C.,Baran, Enrique J.. "Vibrational spectra of the Ga(III) complexes with oxine and clioquinol". . p. 1762 - 1765. Retrieved 2011/10/03.
• 2、 Schlaf,Schroeder,Nelson,Parkinson,Merritt,Crisafulli,Murata,Kafafi. "Determination of interface dipole and band bending at the Ag/tris (8-hydroxyquinolinato) gallium organic Schottky contact by ultraviolet photoemission spectroscopy". . p. 142 - 152. Retrieved 2008/10/08.