(2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride

Base Information

• Chemical Name: (2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride
• CAS No.: 1244740-57-5
• Molecular Formula: C₁₂H₁₇N₃O*ClH
• Molecular Weight: 255.747
• Mol file: 1244740-57-5.mol

Synonyms:(2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride

Chemical Property of (2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of (2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride

There total 1 articles about (2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dimethylethyl (3S)-3-methyl-4-[(phenylamino)carbonyl]-1-piperazinecarboxylate (1244740-07-5) → (2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride (1244740-57-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 5h;

Reference yield: 10.0%

(2S)-2-methyl-N-phenyl-1-piperazinecarboxamide hydrochloride (1244740-57-5) + 4-chlorobenzenesulfonyl chloride (98-60-2) → (2S)-4-[(4-chlorophenyl)sulfonyl]-2-methyI-N-phenyl-1-piperazinecarboxamide (1244740-56-4)

Guidance literature:

In pyridine; at 20 ℃; for 18h; Inert atmosphere;

upstream raw materials:

1,1-dimethylethyl (3S)-3-methyl-4-[(phenylamino)carbonyl]-1-piperazinecarboxylate

Downstream raw materials:

(2S)-4-[(4-chlorophenyl)sulfonyl]-2-methyI-N-phenyl-1-piperazinecarboxamide