4-Acetyl-1lambda6-thiane-1,1-dione

Base Information

Chemical Name:4-Acetyl-1lambda6-thiane-1,1-dione
CAS No.:473254-30-7
Molecular Formula:C₇H₁₂O₃S
Molecular Weight:176.236
Hs Code.:
European Community (EC) Number:837-340-1

Synonyms:473254-30-7;4-acetyl-1lambda6-thiane-1,1-dione;1-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)ethanone;1-(1,1-dioxothian-4-yl)ethanone;MFCD21775912;4-acetyl-1??-thiane-1,1-dione;4-Acetyl-1-thiane-1,1-dione;SCHEMBL12436094;4-acetyl-1|E?-thiane-1,1-dione;AKOS015784694;AT13040;BS-46454;SY160666;DB-373201;CS-0199433;4-ethanoyltetrahydro-2h-thiopyran-1,1-dioxide;EN300-155702;1-(Tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)ethanone;1-(1,1-DIOXIDOTETRAHYDRO-2H-THIOPYRAN-4-YL)ETHAN-1-ONE

Suppliers and Price of 4-Acetyl-1lambda6-thiane-1,1-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Acetyl-1lambda6-thiane-1,1-dione

Chemical Property:

XLogP3:-0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:176.05071541
Heavy Atom Count:11
Complexity:233

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1CCS(=O)(=O)CC1

Technology Process of 4-Acetyl-1lambda6-thiane-1,1-dione

There total 2 articles about 4-Acetyl-1lambda6-thiane-1,1-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.52%

: 75-16-1
methylmagnesium bromide

: N-methoxy-N-methyltetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide

: 473254-30-7
4-acetyl-1λ6-thiane-1,1-dione

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 64096-87-3
1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-carboxylic acid

: 473254-30-7
4-acetyl-1λ6-thiane-1,1-dione

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 16 h / 20 °C

2: tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield: 44.0%

: 589-87-7
1,4-bromoiodobenzene

: 473254-30-7
4-acetyl-1λ6-thiane-1,1-dione

: 1416910-08-1
1-(4-bromo-phenyl)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-ethanol

Guidance literature:: 1,4-bromoiodobenzene; With ethylmagnesium bromide; In tetrahydrofuran; diethyl ether; at -45 - -10 ℃; for 2h;

4-acetyl-1λ6-thiane-1,1-dione; In tetrahydrofuran; diethyl ether; at -70 - 20 ℃; for 16h;