4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene

Base Information

• Chemical Name: 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene
• CAS No.: 1245550-59-7
• Molecular Formula: C₁₆H₂₀N₂O₄
• Molecular Weight: 304.346
• Mol file: 1245550-59-7.mol

Synonyms:4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene

Chemical Property of 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene

There total 1 articles about 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

t-butoxycarbonylhydrazine (870-46-2) + ethyl 3-oxo-3-phenylpropionate (94-02-0) → 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene (1245550-59-7)

Guidance literature:

t-butoxycarbonylhydrazine; ethyl 3-oxo-3-phenylpropionate; With toluene-4-sulfonic acid; In tetrahydrofuran; at 20 ℃;

With sulfuryl dichloride; In dichloromethane; at 20 ℃; for 0.5h;

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.0833333h;

DOI:10.1002/ejoc.201000434

Reference yield: 62.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene (1245550-59-7) + 1-amino-2-propene (107-11-9,30551-89-4) → ethyl 3-allyl-5-phenyl-3H-imidazole-4-carboxylate (1245550-58-6)

Guidance literature:

4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene; 1-amino-2-propene; In acetonitrile; at 20 ℃;

formaldehyd; In acetonitrile; at 150 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1002/ejoc.201000434

Reference yield: 57.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene (1245550-59-7) + benzylamine (100-46-9) → methyl 3-benzyl-5-phenyl-3H-imidazole-4-carboxylate (1245550-57-5)

Guidance literature:

4-ethoxycarbonyl-3-phenyl-1-tert-butoxycarbonyl-1,2-diaza-1,3-diene; benzylamine; In acetonitrile; at 20 ℃;

formaldehyd; In acetonitrile; at 150 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1002/ejoc.201000434

upstream raw materials:

t-butoxycarbonylhydrazine

ethyl 3-oxo-3-phenylpropionate

Downstream raw materials:

ethyl 3-allyl-5-phenyl-3H-imidazole-4-carboxylate

methyl 3-benzyl-5-phenyl-3H-imidazole-4-carboxylate

tert-butyl 2-{[3-butyl-1-(4-chlorophenyl)-2,5-dioxoimidazolidin-4-yl](phenyl)methylene}hydrazinecarboxylate

diethyl 1-benzyl-2-methyl-5-phenyl-1H-pyrrole-3,4-dicarboxylate