N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

Base Information

Chemical Name:N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide
CAS No.:1024589-49-8
Molecular Formula:C₁₈H₁₇BrClN₅O
Molecular Weight:434.723
Hs Code.:

Synonyms:N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

Chemical Property:

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Technology Process of N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

There total 1 articles about N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1024589-35-2
5-bromo-4-(1-cyclopentylhydrazino)-2-pyrimidinecarbonitrile

: 876-08-4
p-(chloromethyl)benzoyl chloride

: 1024589-49-8
N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 496808-04-9
4-[(1-methyl-4-piperidinyl)methyl]piperazine

: 1024589-49-8
N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

: 76-05-1
trifluoroacetic acid

: 1024587-70-9
N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-4-({4-[(1-methyl-4-piperidinyl)methyl]-1-piperazinyl}methyl)benzohydrazide trifluoroacetate

Guidance literature:: 4-[(1-methyl-4-piperidinyl)methyl]piperazine; N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide; With N-ethyl-N,N-diisopropylamine; sodium iodide; In acetonitrile; at 20 - 50 ℃;

trifluoroacetic acid; In water; acetonitrile;

Reference yield:

: 63214-56-2
(4-methyl-piperazin-1-yl)-piperidin-4-yl-methanone

: 1024589-49-8
N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide

: 76-05-1
trifluoroacetic acid

: 1024587-74-3
N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-4-({4-[(4-methyl-1-piperazinyl)carbonyl]-1-piperidinyl}methyl)benzohydrazide trifluoroacetate

Guidance literature:: (4-methyl-piperazin-1-yl)-piperidin-4-yl-methanone; N'-(5-bromo-2-cyano-4-pyrimidinyl)-4-(chloromethyl)-N'-cyclopentylbenzohydrazide; With N-ethyl-N,N-diisopropylamine; sodium iodide; In acetonitrile; at 20 - 50 ℃;

trifluoroacetic acid; In water; acetonitrile;