63214-56-2

Usage

Uses

Used in Scientific Research:
(4-Methyl-piperazin-1-yl)-piperidin-4-yl-methanone 2 HCL is used as a chemical compound for various scientific research applications. Its unique structure and properties make it a potential candidate for studying chemical reactions and interactions.
Used in Industrial Applications:
(4-Methyl-piperazin-1-yl)-piperidin-4-yl-methanone 2 HCL is used as a chemical intermediate in the synthesis of other compounds for industrial purposes. Its solubility in water due to the hydrochloride groups may facilitate its use in aqueous reactions, making it a valuable component in the production of various industrial products.
Used in Pharmaceutical Development:
(4-Methyl-piperazin-1-yl)-piperidin-4-yl-methanone 2 HCL is used as a potential pharmaceutical candidate for the development of new drugs. Its unique structure and properties may offer opportunities for the creation of novel therapeutic agents, particularly in the fields of medicinal chemistry and drug discovery.

InChI:InChI=1/C11H21N3O/c1-13-6-8-14(9-7-13)11(15)10-2-4-12-5-3-10/h10,12H,2-9H2,1H3

Upstream product

• 1013330-07-8 (1-benzylpiperidin-4-yl)(4-methylpiperazin-1-yl)methanone 
• 109-01-3 1-methyl-piperazine 
• 10314-98-4 1-benzyloxycarbonylpiperidine-4-carboxylic acid 
• 1612250-64-2 C₁₉H₂₇N₃O₃ 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 

Downstream Products

• 1024587-74-3 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-4-({4-[(4-methyl-1-piperazinyl)carbonyl]-1-piperidinyl}methyl)benzohydrazide trifluoroacetate 
• 1024587-80-1 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclopentyl-3-({4-[(4-methyl-1-piperazinyl)carbonyl]-1-piperidinyl}methyl)benzohydrazide trifluoroacetate 
• 1024588-00-8 N'-(5-bromo-2-cyano-4-pyrimidinyl)-N'-cyclohexyl-4-({4-[(4-methyl-1-piperazinyl)carbonyl]-1-piperidinyl}methyl)benzohydrazide trifluoroacetate 
• 735262-46-1 4-[(4-methyl-1-piperazinyl)methyl]piperidine 

Relevant academic research and scientific papers

Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety

We herein report the design and synthesis of benzothiazinones containing a piperidine moiety as new antitubercular agents based on the structure feature of IMB-ZR-1 discovered in our lab. Some of them were found to have good in vitro activity (MIC 1 μg/

A scalable route to the SMO receptor antagonist SEN826: Benzimidazole synthesis via enhanced in situ formation of the bisulfite-aldehyde complex

A practical and scalable route to the SMO antagonist SEN826 1 is described herein, including the discussion of an alternative approach to the synthesis of the target molecule. The optimized route consists of five chemical steps. A new and efficient access to the key intermediate 6 via the bisulfite-aldehyde complex was developed, significantly enhancing the yields and reducing costs. As a result, a synthetic procedure for preparation of multihundred gram quantities of the final product has been developed.

6-PHENYL-2-[((PIPERIDIN-4-YLMETHYL)-PIPERAZIN-1YL) OR PIPERAZIN 1-YLMETHYL)-PIPERIDIN-1-YL)]-IMIDAZO[2,1-B][1,3,4]THIADIAZOLE DERIVATIVES AND THEIR USE

The present invention is directed to novel heterocyclic compounds, their synthesis and pharmaceutical compositions comprising them for the treatment of disorders, in particular, cancer.