(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Base Information

Chemical Name:(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide
CAS No.:905730-24-7
Molecular Formula:C₁₄H₂₂ClNOS
Molecular Weight:287.854
Hs Code.:

(R<sub>S</sub>,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Synonyms:(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Suppliers and Price of (R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

There total 1 articles about (R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 905730-16-7
(R_S)-(-)-N-(2-chloro-2-methyl-1-propylidene)-tert-butanesulfinamide

: 100-59-4
phenylmagnesium chloride

: 905730-24-7
(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

Guidance literature:: In tetrahydrofuran; dichloromethane; at -97 - -78 ℃;
DOI:10.1021/ol0611245

Reference yield: 73.0%

: 905730-24-7
(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

: (R_S,3R)-(-)-N-(tert-butylsulfinyl)-3-phenyl-2,2-dimethylaziridine

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; water; at 50 ℃; for 24h;
DOI:10.1021/ol0611245

Reference yield:

: 905730-24-7
(R_S,1R)-(-)-N-(2-chloro-2-methyl-1-phenylpropyl)-tert-butanesulfinamide

: (3R)-2,2-dimethyl-3-phenylaziridinium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / potassium hydroxide / H₂O; tetrahydrofuran / 24 h / 50 °C

2: HCl*dioxane / dioxane / 0.08 h / 20 °C

With potassium hydroxide; hydrochloric acid 1,4-dioxane; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/ol0611245