(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

Base Information

Chemical Name:(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine
CAS No.:121411-08-3
Molecular Formula:C₂₂H₂₃NO₂S
Molecular Weight:365.496
Hs Code.:

Synonyms:(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of (4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

There total 5 articles about (4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1519-39-7
(R)-methyl p-tolyl sulfoxide

: 783-08-4
[4-(benzylideneamino)phenyl]methanol

: 121411-07-2
(1R,(S)R)-N-(p-methoxyphenyl)-1-phenyl-2-(p-tolylsulfinyl)ethylamine

: 121411-08-3
(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, 0 deg C; 2) THF, -78 deg C, 15 min;
DOI:10.1016/S0040-4039(00)82275-3

Reference yield:

: 100-52-7
benzaldehyde

: 121411-07-2
(1R,(S)R)-N-(p-methoxyphenyl)-1-phenyl-2-(p-tolylsulfinyl)ethylamine

: 121411-08-3
(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: Mg₂SO₄ / dichloromethane / 20 °C

2: lithium diisopropyl amide / tetrahydrofuran / -78 °C

With lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acscatal.8b04946

Reference yield:

: 104-94-9
4-methoxy-aniline

: 121411-07-2
(1R,(S)R)-N-(p-methoxyphenyl)-1-phenyl-2-(p-tolylsulfinyl)ethylamine

: 121411-08-3
(4-Methoxy-phenyl)-[(S)-1-phenyl-2-((R)-toluene-4-sulfinyl)-ethyl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: Mg₂SO₄ / dichloromethane / 20 °C

2: lithium diisopropyl amide / tetrahydrofuran / -78 °C

With lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acscatal.8b04946