3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester

Base Information

• Chemical Name: 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester
• CAS No.: 1202273-71-9
• Molecular Formula: C₂₇H₂₉N₃O₂
• Molecular Weight: 427.546
• Mol file: 1202273-71-9.mol

Synonyms:3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester

Chemical Property of 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester

There total 2 articles about 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid methyl ester (1202273-64-0) + isopropyl bromide (75-26-3) → 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester (1202273-71-9)

Guidance literature:

3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid methyl ester; With potassium hydroxide; In ethanol; for 72h; Reflux;

isopropyl bromide; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1021/jm200695m

Reference yield: 68.0%

→ 3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid isopropyl ester (1202273-71-9)

Guidance literature:

upstream raw materials:

3-imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propionic acid methyl ester

isopropyl bromide