(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

Base Information

Chemical Name:(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine
CAS No.:119789-04-7
Molecular Formula:C₃₈H₄₅NO₈P₂
Molecular Weight:705.725
Hs Code.:

Synonyms:(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

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Chemical Property of (2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

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Technology Process of (2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

There total 6 articles about (2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1.6M-n-butyllithium-hexane

: 10177-79-4
bis(2-methoxyphenyl)phosphine

: 119751-62-1
(2S,4S)-N-tert.-butoxycarbonyl-4-bis(4-methoxyphenyl)phosphinyl-2-tosyloxymethylpyrrolidine

: 119789-04-7
(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

Guidance literature:: With sodium chloride; dihydrogen peroxide; sodium hydrogencarbonate; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

Reference yield:

: 39864-55-6
Lithium-di-(p-anisyl)-phosphid

: 119789-04-7
(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) 10percent H₂O₂

2: 1.) n-Bu₄NF

3: 2.) 10percent H₂O₂

With tetrabutyl ammonium fluoride; dihydrogen peroxide;

Reference yield:

: 61478-26-0
tert-butyl (2S,4R)-4-hydroxy-2-hydroxymethyl-pyrrolidine-1-carboxylate

: 119789-04-7
(2S,4S)-N-tert.-butoxycarbonyl-2-bis(2-methoxyphenyl)phosphinylmethyl-4-bis(4-methoxyphenyl)phosphinylpyrrolidine

Guidance literature:: Multi-step reaction with 4 steps

2: 2.) 10percent H₂O₂

3: 1.) n-Bu₄NF

4: 2.) 10percent H₂O₂

With tetrabutyl ammonium fluoride; dihydrogen peroxide;