Technology Process of 3,3-dimethylanagrelide tosylate
There total 5 articles about 3,3-dimethylanagrelide tosylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
acetone;
at 58 ℃;
Industry scale;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sulfuric acid / 3.5 h / 20 - 44 °C / Industry scale
1.2: 4 h / 16 - 28 °C
2.1: triethylamine / toluene / 8.92 h / 17 - 110 °C / Industry scale
3.1: sodium tetrahydroborate; acetic acid / toluene / 13.58 h / 0 - 30 °C / Industry scale
4.1: hydrogen / platinum on carbon / methanol / 7 h / 20 - 27 °C / 1500.15 Torr / Inert atmosphere; Industry scale
5.1: methanol / 10 h / 20 - 64 °C / Industry scale
6.1: acetone / 58 °C / Industry scale
With
sodium tetrahydroborate; sulfuric acid; hydrogen; acetic acid; triethylamine;
platinum on carbon;
In
methanol; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / toluene / 8.92 h / 17 - 110 °C / Industry scale
2: sodium tetrahydroborate; acetic acid / toluene / 13.58 h / 0 - 30 °C / Industry scale
3: hydrogen / platinum on carbon / methanol / 7 h / 20 - 27 °C / 1500.15 Torr / Inert atmosphere; Industry scale
4: methanol / 10 h / 20 - 64 °C / Industry scale
5: acetone / 58 °C / Industry scale
With
sodium tetrahydroborate; hydrogen; acetic acid; triethylamine;
platinum on carbon;
In
methanol; acetone; toluene;
