(R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

Base Information

Chemical Name:(R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol
CAS No.:447461-94-1
Molecular Formula:C₁₉H₃₅NO₃Si
Molecular Weight:353.577
Hs Code.:

Synonyms:(R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

Suppliers and Price of (R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

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Technology Process of (R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

There total 10 articles about (R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: C₂₆H₃₉NO₄Si

: 447461-94-1
(R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

Guidance literature:: With ammonium chloride; methyllithium; In diethyl ether; water; at 0 ℃; for 0.0833333h;

Reference yield: 48.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 447462-08-0
(R)-4-oxo-2-(4-dimethylamino-2-methoxyphenyl)-butyric acid methyl ester

: 447461-94-1
(R)-4-tert-butyldimethylsilyloxy-2-(4-dimethylamino-2-methoxy-phenyl)-butanol

Guidance literature:: (R)-4-oxo-2-(4-dimethylamino-2-methoxyphenyl)-butyric acid methyl ester; With sodium tetrahydroborate; In ethanol; dichloromethane; at 0 ℃; for 0.0833333h;

tert-butyldimethylsilyl chloride; With dmap; triethylamine; In dichloromethane; for 1h;

With lithium aluminium tetrahydride; Rochelle's salt; In diethyl ether; water; at 0 ℃; for 8.08333h;