(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate

Base Information

• Chemical Name: (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate
• CAS No.: 1198053-79-0
• Molecular Formula: C₂₂H₂₇NO₃S
• Molecular Weight: 385.527
• Mol file: 1198053-79-0.mol

Synonyms:(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate

Chemical Property of (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate

There total 1 articles about (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-methylpropane-2-sulfinic acid [1-(2-methyl-1-ylphenyl)ethylidene]amide (1208989-34-7) + (E)-3-bromoprop-1-enyl benzoate (500756-90-1) → (1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate (1198053-79-0)

Guidance literature:

With zinc; In N,N,N,N,N,N-hexamethylphosphoric triamide; water; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/chem.200900801

Reference yield:

(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate (1198053-79-0) + acetic anhydride (108-24-7) → C20H21NO3 (1198054-00-0)

Guidance literature:

(1S,2R)-1-((R)-1,1-dimethylethylsulfinamido)-1-o-tolylbut-3-en-2-yl benzoate; With hydrogenchloride; methanol; at 20 ℃;

acetic anhydride; With dmap; triethylamine; In dichloromethane; at 20 ℃; optical yield given as %ee;

DOI:10.1002/chem.200900801

upstream raw materials:

2-methylpropane-2-sulfinic acid [1-(2-methyl-1-ylphenyl)ethylidene]amide

(E)-3-bromoprop-1-enyl benzoate

Downstream raw materials:

C₂₀H₂₁NO₃