3,3-Diphenylpropionic acid

Base Information

Chemical Name:3,3-Diphenylpropionic acid
CAS No.:606-83-7
Molecular Formula:C15H14O2
Molecular Weight:226.275
Hs Code.:29163990
European Community (EC) Number:210-125-4
NSC Number:631492,6797
UNII:8N5P6K2EGB
DSSTox Substance ID:DTXSID1060554
Nikkaji Number:J23.152E
Wikidata:Q63392248
ChEMBL ID:CHEMBL1897989
Mol file:606-83-7.mol

Synonyms:3,3-diphenylpropanoate

Suppliers and Price of 3,3-Diphenylpropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,3-Diphenylpropionic Acid
100g
$ 130.00

TCI Chemical
3,3-Diphenylpropionic Acid >97.0%(T)
25g
$ 116.00

SynQuest Laboratories
3,3-Diphenylpropionic acid
100 g
$ 263.00

Sigma-Aldrich
3,3-Diphenylpropionic acid 99%
100g
$ 134.00

Sigma-Aldrich
3,3-Diphenylpropionic acid 99%
25g
$ 56.80

Medical Isotopes, Inc.
3,3-Diphenylpropionic Acid
100 g
$ 680.00

Matrix Scientific
3,3-Diphenylpropionic acid 95%+
1g
$ 101.00

Matrix Scientific
3,3-Diphenylpropionic acid 95%+
5g
$ 323.00

Matrix Scientific
3,3-Diphenylpropionic acid 95%+
2.500g
$ 215.00

Frontier Specialty Chemicals
3,3-Diphenylpropionic Acid 97%
100g
$ 156.00

Total 103 raw suppliers

Chemical Property of 3,3-Diphenylpropionic acid

Chemical Property:

Appearance/Colour:white to light yellow crystalline powder
Melting Point:151-154 °C(lit.)
Refractive Index:1.6530 (estimate)
Boiling Point:358.3 °C at 760 mmHg
PKA:4.45±0.10(Predicted)
Flash Point:255.3 °C
PSA：37.30000
Density:1.147 g/cm³
LogP:3.29320
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Water Solubility.:slightly soluble
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:226.099379685
Heavy Atom Count:17
Complexity:219

Purity/Quality:

99%, ^*data from raw suppliers

3,3-Diphenylpropionic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-24/25-37/39-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CC(=O)O)C2=CC=CC=C2
Uses 3,3-Diphenylpropionic Acid is used in the preparation of steroid 5α-reductase inhibiting acylpiperidines. It can also be used in the preparation of calpain-inhibitory piptidyl α-ketoacids and esters.

Technology Process of 3,3-Diphenylpropionic acid

There total 111 articles about 3,3-Diphenylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 23426-03-1
3,3-diphenylpropanoic acid methyl ester

: 606-83-7
3,3-Diphenylpropionic acid

Guidance literature:: With sodium hydroxide; In methanol; at 60 ℃; Inert atmosphere;
DOI:10.1002/anie.201912584

Reference yield: 97.0%

: 621-82-9
Cinnamic acid

: 98-80-6
phenylboronic acid

: 606-83-7
3,3-Diphenylpropionic acid

Guidance literature:: With [2,2]bipyridinyl; palladium diacetate; acetic acid; In tetrahydrofuran; water; at 80 ℃; for 24h; Solvent; Schlenk technique;
DOI:10.1021/acs.joc.7b01248

Reference yield: 96.0%

: 140-10-3
(E)-3-phenylacrylic acid

: 98-80-6
phenylboronic acid

: 606-83-7
3,3-Diphenylpropionic acid

Guidance literature:: With dichloro(2,2'-bipyridine)palladium(II); silver nitrate; In water; at 60 ℃; for 10h; Reagent/catalyst; Temperature; Green chemistry;
DOI:10.1016/j.tetlet.2018.02.013