Ethyl (R)-2-Hydroxy-4-phenylbutyrate

Base Information

Chemical Name:Ethyl (R)-2-Hydroxy-4-phenylbutyrate
CAS No.:90315-82-5
Molecular Formula:C12H16O3
Molecular Weight:208.257
Hs Code.:29181990
European Community (EC) Number:618-525-4
UNII:QP7IWH2QOX
DSSTox Substance ID:DTXSID20370015
Nikkaji Number:J275.578E
ChEMBL ID:CHEMBL4630646
Mol file:90315-82-5.mol

Synonyms:(R)-HPBE;ethyl (R)-2-hydroxy-4-phenylbutyrate

Suppliers and Price of Ethyl (R)-2-Hydroxy-4-phenylbutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-Hydroxy-4-phenylbutyricAcidEthylEster
5g
$ 95.00

TCI Chemical
Ethyl (R)-2-Hydroxy-4-phenylbutyrate >98.0%(GC)
5g
$ 17.00

Sigma-Aldrich
Ethyl (R)-(?)-2-hydroxy-4-phenylbutyrate 98%
5g
$ 37.00

Sigma-Aldrich
Ethyl (R)-(?)-2-hydroxy-4-phenylbutyrate ChiPros?, produced by BASF, 98%
5 g
$ 180.00

Sigma-Aldrich
Ethyl (R)-()-2-hydroxy-4-phenylbutyrate ChiPros , produced by BASF, 98%
25g
$ 765.00

Frontier Specialty Chemicals
Ethyl (R)-()-2-hydroxy-4-phenylbutyrate 98%
25g
$ 458.00

Frontier Specialty Chemicals
Ethyl (R)-()-2-hydroxy-4-phenylbutyrate 98%
5g
$ 112.00

Crysdot
(R)-HPBE 95+%
100g
$ 185.00

Crysdot
(R)-HPBE 95+%
25g
$ 57.00

Chem-Impex
Ethyl(R)-(-)-2-hydroxy-4-phenylbutyrate,97.5%(GC) 97.5%(GC)
5G
$ 85.12

Total 127 raw suppliers

Chemical Property of Ethyl (R)-2-Hydroxy-4-phenylbutyrate

Chemical Property:

Appearance/Colour:colorless to light yellow liquid
Vapor Pressure:6.44E-05mmHg at 25°C
Melting Point:NA
Refractive Index:n20/D 1.504(lit.)
Boiling Point:330.9 °C at 760 mmHg
PKA:13.00±0.20(Predicted)
Flash Point:137.6 °C
PSA：46.53000
Density:1.098 g/cm³
LogP:1.54320
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:insoluble
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:208.109944368
Heavy Atom Count:15
Complexity:185

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-Hydroxy-4-phenylbutyricAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CCC1=CC=CC=C1)O
Isomeric SMILES:CCOC(=O)[C@@H](CCC1=CC=CC=C1)O
Uses Ethyl(R)-2-hydroxy-4-phenylbutyrate is used in the preparation of benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia. Ethyl (R)-(?)-2-hydroxy-4-phenylbutyrate can be used as a key intermediate for the synthesis of various ACE inhibitors like Cilazapril, Benazepril, and Enalapril.

Technology Process of Ethyl (R)-2-Hydroxy-4-phenylbutyrate

There total 63 articles about Ethyl (R)-2-Hydroxy-4-phenylbutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 244277-48-3
ethyl (R)-(-)-2-hydroxy-4-oxo-4-phenylbutanoate

: 90315-82-5
ethyl (R)-2-hydroxy-4-phenylbutyrate

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 5.5h; under 825.066 Torr;
DOI:10.1016/S0040-4020(00)00617-7