Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate

Base Information

Chemical Name:Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate
CAS No.:5446-19-5
Molecular Formula:C13H15 N O5
Molecular Weight:265.2619
Hs Code.:
NSC Number:17187
DSSTox Substance ID:DTXSID40280501
Wikidata:Q82013868

Synonyms:5446-19-5;methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate;Methyl 2-(acetyl(2-methoxy-2-oxoethyl)amino)benzoate;NSC17187;DTXSID40280501;NSC 17187;NSC-17187

Suppliers and Price of Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate

Chemical Property:

Vapor Pressure:6.36E-07mmHg at 25°C
Boiling Point:409.7°Cat760mmHg
Flash Point:201.6°C
Density:1.231g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:265.09502258
Heavy Atom Count:19
Complexity:355

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(CC(=O)OC)C1=CC=CC=C1C(=O)OC

Technology Process of Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate

There total 3 articles about Methyl 2-[acetyl(2-methoxy-2-oxoethyl)amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 13622-59-8
N-(2-methoxycarbonylphenyl)glycine methyl ester

: 108-24-7
acetic anhydride

: 5446-19-5
methyl 2-(N-(2-methoxy-2-oxoethyl)acetamido)benzoate

Guidance literature:: With sulfuric acid; at 100 ℃; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.6b03473

Reference yield:

: 134-20-3
2-carbomethoxyaniline

: 5446-19-5
methyl 2-(N-(2-methoxy-2-oxoethyl)acetamido)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 12 h / 80 °C / Inert atmosphere; Sealed tube

2: sulfuric acid / 100 °C / Inert atmosphere; Sealed tube

With sulfuric acid; In N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.6b03473