2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose

Base Information

• Chemical Name: 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose
• CAS No.: 140926-89-2
• Molecular Formula: C₆₂H₆₄Cl₂O₁₁
• Molecular Weight: 1056.09

Synonyms:2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose

Chemical Property of 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose

There total 2 articles about 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

dichloromethane (75-09-2) + 2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-D-glucono-1,5-lactone (88970-25-6) → 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose (140926-89-2)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -75 - -70 ℃; for 1h;

DOI:10.1021/jo00039a026

Reference yield:

2,3,6-tris-O-(phenylmethyl)-4-O-[2,3,4,6-tetrakis-O-(phenylmethyl)-β-D-glucopyranosyl]-D-glucopyranoside (148968-90-5) → 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose (140926-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Ac₂O, DMSO / 20 h / Ambient temperature

2: 94 percent / LDA / tetrahydrofuran / 1 h / -75 - -70 °C

With acetic anhydride; dimethyl sulfoxide; lithium diisopropyl amide; In tetrahydrofuran;

DOI:10.1021/jo00039a026

Reference yield: 87.0%

2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose (140926-89-2) → (1R)-2,3,6-Tri-O-benzyl-1-C-(dichloromethyl)-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-D-glucitol (140926-90-5)

Guidance literature:

With sodium tetrahydroborate; In diethylene glycol dimethyl ether; Ambient temperature;

DOI:10.1021/jo00039a026

upstream raw materials:

dichloromethane

2,3,6-tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-D-glucono-1,5-lactone

2,3,6-tris-O-(phenylmethyl)-4-O-[2,3,4,6-tetrakis-O-(phenylmethyl)-β-D-glucopyranosyl]-D-glucopyranoside

Downstream raw materials:

(1R)-2,3,6-Tri-O-benzyl-1-C-(dichloromethyl)-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-D-glucitol

(1S)-(1(OH),2,4/1,3)-3,4-Di-O-benzyl-1-C-<(benzyloxy)methyl>-2-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-oxo-1,2,3,4-cyclohexanetetrol

(1S)-(1(OH),2,4/1,3)-3,4-Di-O-benzyl-1-C-<(benzyloxy)methyl>-2-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-6,6-dichloro-5-oxo-1,2,3,4-cyclohexanetetrol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 140926-89-2 2,3,6-Tri-O-benzyl-4-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-1-C-(dichloromethyl)-α-D-glucopyranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send