2-cyano-3-phenylaziridine

Base Information

• Chemical Name: 2-cyano-3-phenylaziridine
• CAS No.: 66913-75-5
• Molecular Formula: C₉H₈N₂
• Molecular Weight: 144.176
• Mol file: 66913-75-5.mol

Synonyms:2-cyano-3-phenylaziridine

Chemical Property of 2-cyano-3-phenylaziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-cyano-3-phenylaziridine

There total 13 articles about 2-cyano-3-phenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

α,β-dibromo-β-phenylpropionitrile (19521-13-2) → 2-cyano-3-phenylaziridine (66913-75-5)

Guidance literature:

With ammonia; In dimethyl sulfoxide; Ambient temperature;

DOI:10.1016/S0022-1139(00)82305-2

Reference yield: 70.0%

α,β-dibromocinnamonitrile (88286-26-4) → cis-(+/-)-3-phenylaziridine-2-carbonitrile (64300-27-2,66913-75-5,80375-47-9)

Guidance literature:

With ammonia; In dimethyl sulfoxide; for 12h; Ambient temperature;

Reference yield: 63.0%

(Z)-3-amino-3-phenylacrylonitrile (17196-74-6) → 2-cyano-3-phenylaziridine (66913-75-5)

Guidance literature:

With (PhIO)n; at 0 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2019.05.045

upstream raw materials:

α,β-dibromo-β-phenylpropionitrile

cinnamic nitrile

(Z)-3-amino-3-phenylacrylonitrile

α,β-dibromocinnamonitrile

Downstream raw materials:

erythro-2-amino-3-fluoro-3-phenylpropionitrile

threo-2-amino-3-fluoro-3-phenylpropiononitrile

3-fluoro-3-phenylalanine

erythro-3-fluoro-3-phenylalanine