17196-74-6

Basic information

• Product Name: (Z)-3-amino-3-phenylacrylonitrile
• Synonyms: (Z)-3-amino-3-phenylacrylonitrile
• CAS NO: 17196-74-6
• Molecular Weight: 144.176
• Mol File: 17196-74-6.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: (Z)-3-amino-3-phenylacrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-amino-3-phenylacrylonitrile(17196-74-6)
• EPA Substance Registry System: (Z)-3-amino-3-phenylacrylonitrile(17196-74-6)

Safety Data

• Hazardous Substances Data: 17196-74-6(Hazardous Substances Data)

Upstream product

• 100-47-0 benzonitrile 
• 75-05-8 acetonitrile 
• 3755-96-2 (2Z)-3-bromo-3-phenylprop-2-enenitrile 
• 99749-00-5 lithioacetonitrile 
• 60-29-7 diethyl ether 
• 536-74-3 phenylacetylene 
• 140-29-4 phenylacetonitrile 
• 614-16-4 Benzoylacetonitrile 
• 33440-88-9 silver phenylacetylide 
• 73789-56-7 N-isocyaniminotriphenylphosphorane 
• 14904-36-0 cis-trans-3--cinnamonitril 
• 14904-42-8 cis-trans-3-Trimethylsilylamino-cinnamonitril 

Downstream Products

• 21628-33-1 6-amino-3-cyano-2,4-diphenylpyridine 
• 7758-73-8 5,7-dihydroxy-4-phenyl-2H-1-benzopyran-2-one 
• 861318-51-6 4-chloromethyl-2,6-diphenyl-1,4-dihydro-pyridine-3,5-dicarbonitrile 
• 33831-53-7 4-hydroxy-6-methyl-2-phenyl-nicotinonitrile 
• 452070-10-9 4-methyl-2-phenyl-quinoline-3-carbonitrile 
• 1563-41-3 2-(α-amino-benzyliden)-5-oxo-hex-3-enenitrile 
• 853916-48-0 4-(2-methoxy-phenyl)-2,6-diphenyl-1,4-dihydro-pyridine-3,5-dicarbonitrile 
• 846550-70-7 5-cyano-2-methyl-6-phenyl-nicotinic acid ethyl ester 
• 412337-54-3 5-cyano-6-phenyl-pyridine-2,3-dicarboxylic acid diethyl ester 
• 2555-30-8 7-hydroxy-4-phenylcoumarin 
• 69316-11-6 α-hydroximido-(2-benzoyl)acetonitrile 

Relevant articles and documents

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Tandem Thorpe Reaction/Palladium Catalyzed Asymmetric Allylic Alkylation: Access to Chiral β-enaminonitriles with Excellent Enantioselectivity

A new type of nucleophile, a 3-imino nitrile carbanion generated in situ by Thorpe reaction of acetonitrile with a base, was developed successfully and applied in a Pd-catalyzed asymmetric allylic alkylation with mono-substituted allyl reagents under Pd/S

Green synthesis method of nicotinic acid ester compounds based on non-metallic conditions

The invention discloses a green synthesis method based on nicotinic acid ester compounds under non-metallic conditions, and belongs to the technical field of organic synthesis. The method comprises the following steps of (III) replacing cyclopropanol and (II) substituted enamine ester as a raw material, taking tetramethyl piperidine nitrogen oxide as an oxidizing agent, 110 - 130 °C, stirring and reacting in an organic solvent to synthesize a (I) nicotinate compound. The invention provides a green synthesis method based on nicotinic acid ester compounds under non-metallic conditions, wherein cyclopropanols and enamine esters are taken as raw materials, and a polysubstituted nicotinate is synthesized through a strategy of oxidative dehydrogenation of ketene cyclization.

Silver-promoted regio- and stereoselective aminocyanation of alkynes for the synthesis of β-aminoacrylonitriles using N-isocyanoiminotriphenylphosphorane

The silver-promoted intermolecular aminocyanation of alkynes for the synthesis of (Z)-β-aminoacrylonitriles is reported, using N-isocyanoiminotriphenylphosphorane (NIITP) as both the nitrile and amine source. The transformation proceeds in moderate to good yields, and in a regio- and stereoselective manner, using a wide range of acetylenes.