C₂₁H₁₅IN₂O

Base Information

• Chemical Name: C₂₁H₁₅IN₂O
• CAS No.: 957785-24-9
• Molecular Formula: C₂₁H₁₅IN₂O
• Molecular Weight: 438.267
• Mol file: 957785-24-9.mol

Synonyms:C₂₁H₁₅IN₂O

Chemical Property of C₂₁H₁₅IN₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₁₅IN₂O

There total 4 articles about C₂₁H₁₅IN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

C21H16N2O (957785-23-8) → C21H15IN2O (957785-24-9)

Guidance literature:

With Iodine monochloride; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

DOI:10.1021/jo701435p

Reference yield:

(E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one (957785-22-7) → C21H15IN2O (957785-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / potassium tert-butoxide / dimethylsulfoxide / 3.5 h / 95 °C

2: 67 percent / potassium carbonate; iodine monochloride / dimethylformamide / 15 h / 20 °C

With potassium tert-butylate; Iodine monochloride; potassium carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1021/jo701435p

Reference yield:

1-quinolin-2-yl-ethanone (1011-47-8) → C21H15IN2O (957785-24-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaOH / ethanol / 0.08 h / 20 °C

1.2: 83 percent / ethanol / 2 h / 20 °C

2.1: 100 percent / potassium tert-butoxide / dimethylsulfoxide / 3.5 h / 95 °C

3.1: 67 percent / potassium carbonate; iodine monochloride / dimethylformamide / 15 h / 20 °C

With sodium hydroxide; potassium tert-butylate; Iodine monochloride; potassium carbonate; In ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1021/jo701435p

upstream raw materials:

C₂₁H₁₆N₂O

(E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one

1-quinolin-2-yl-ethanone

benzaldehyde