957785-22-7

Basic information

• Product Name: (E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one
• Synonyms: (E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one
• CAS NO: 957785-22-7
• Molecular Weight: 259.307
• Mol File: 957785-22-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one(957785-22-7)
• EPA Substance Registry System: (E)-3-phenyl-1-(quinolin-2-yl)prop-2-en-1-one(957785-22-7)

Safety Data

• Hazardous Substances Data: 957785-22-7(Hazardous Substances Data)

Upstream product

• 5470-96-2 quinoline 2-carbaldehyde 
• 536-74-3 phenylacetylene 
• 1011-47-8 1-quinolin-2-yl-ethanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 957785-23-8 C₂₁H₁₆N₂O 
• 957785-24-9 C₂₁H₁₅IN₂O 

Relevant articles and documents

Synthetic and mechanistic studies on the solvent-dependent copper-catalyzed formation of indolizines and chalcones

Copper nanoparticles supported on activated carbon have been found to catalyze the multicomponent synthesis of indolizines from pyridine-2-carbaldehyde derivatives, secondary amines, and terminal alkynes in dichloromethane; in the absence of solvent, howe

Total synthesis of streptonigrone

(Chemical Equation Presented) A total synthesis of streptonigrone, 1, is described, which incorporates a one-step synthesis of substituted pyridones devised in our laboratory. Other aspects of the synthesis that differentiate the present approach from previous ones are the use of a Conrad-Limpach reaction, rather than the customary Friedlaender methodology, to assemble the quinoline segment of 1, and the implementation of an anionic sequence for the functionalization of a key pyridone intermediate.