5-(4-bromomethylphenyl)-5-oxomethylpentanoate

Base Information

• Chemical Name: 5-(4-bromomethylphenyl)-5-oxomethylpentanoate
• CAS No.: 882426-94-0
• Molecular Formula: C₁₃H₁₅BrO₃
• Molecular Weight: 299.164
• Mol file: 882426-94-0.mol

Synonyms:5-(4-bromomethylphenyl)-5-oxomethylpentanoate

Chemical Property of 5-(4-bromomethylphenyl)-5-oxomethylpentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 5-(4-bromomethylphenyl)-5-oxomethylpentanoate

There total 4 articles about 5-(4-bromomethylphenyl)-5-oxomethylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-(chlorocarbonyl)butyrate (1501-26-4) + benzyl bromide (100-39-0) → 5-(4-bromomethylphenyl)-5-oxomethylpentanoate (882426-94-0)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 ℃; for 3h;

Reference yield:

5-(p-tolyl)-5-oxopentanoic acid methyl ester (93390-44-4) → 5-(4-bromomethylphenyl)-5-oxomethylpentanoate (882426-94-0)

Guidance literature:

With N-Bromosuccinimide;

DOI:10.1021/ja00401a053

Reference yield:

methyl 4-(chlorocarbonyl)butyrate (1501-26-4) → 5-(4-bromomethylphenyl)-5-oxomethylpentanoate (882426-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Friedel-Crafts conditions

2: N-bromosuccinimide

With N-Bromosuccinimide;

DOI:10.1021/ja00401a053

upstream raw materials:

5-(p-tolyl)-5-oxopentanoic acid methyl ester

methyl 4-(chlorocarbonyl)butyrate

toluene

benzyl bromide

Downstream raw materials:

methyl 5-(4-bromomethylphenyl)pentanoate